Protein Alignment SLC22A and LOC1280331

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_061517658.1
• Gene: LOC1280331 / 1280331
• VectorBaseID: AGAMI1_006734
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 235/548 - (42%)
• Similarity: 348/548 - (63%)
• Gaps: 35/548 - (6%)

  Fly    17 PPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLP 81
            |.|:|  ||.||.:|..:|||||||:..:.|:.||::|:|:|:::|:|||..:.:||.|.||:.|
Mosquito     2 PQAED--DVDLDGVLHEIGQFGRFQVRQYGLMVLPIIFNALFTLSYIFTAGNLEYRCLVPECEDP 64

  Fly    82 GSNYYEP---HTNWS--IPKNGKDLDSCNRY----TNSELPQWNHSVDICSADHFTKNKEA---C 134
            .::.|.|   :..|.  :..:|:    |.|.    .::.||:..     |::|.|  |..|   |
Mosquito    65 ATDVYNPPWLNATWPGLLHSDGR----CQRLQFISNDTRLPEGE-----CTSDDF--NTSAIIPC 118

  Fly   135 AHNEFVFRDDEVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGI 198
              :.|||:.:|.||..||.|.| .::|||::||||||:|||..:||.|:::||:||.:.:.:...
Mosquito   119 --DAFVFQTEESTIVRDFNITCAHNDWKLTLVGTINNVGQFVALPIAGYLSDRFGRRWILLVSVA 181

  Fly   199 LGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEV 263
            ..|:.|::|||:.||..|:..||||.:..||:|:|.|::.:||||||.||...::|:..::.||.
Mosquito   182 GSALFGLVRSFATSYEMFIAMEFLDPVIGSTMYTTAFILALELVGPKMRVTGNNIISCAFSFGEA 246

  Fly   264 LLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELP 328
            ||.:.|..|.|||:||||.|.|.|:.|.:.:...||||||||:.:::.|..||:|||.:|.:.:.
Mosquito   247 LLGLLAMYFRDWRVLLRILYIPGLLALPFLYTTVESVRWLLSKNRKDEAFTILKRAAKLNGKTIS 311

  Fly   329 ESVLDKL-VLANRDKLQQSSESRF---PIREAFKN--FKWRIANCSLCWIVHVLVYYGLSLNVVL 387
            ::..::. .:..:....:|.:::.   .:|||..|  ...|:.|||.||:.:.:||:|||||.|.
Mosquito   312 QAAFERFNCIETKSGSAKSLDTQTYAQLLREALANPALVLRVINCSFCWLTNTMVYFGLSLNSVS 376

  Fly   388 LDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIF-TGADQPVLQLVL 451
            |.|:||.||..::|:|:||||:..||:||.||:.:|...::.|||.||.::| ...|.|.|.|.|
Mosquito   377 LSGNKYLNFILVSLIELPGFFLMQLILDRVGRKKTLFTTLVLSGLFCIISVFIADIDAPALHLTL 441

  Fly   452 FLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFA 516
            ||:.||:||.||..||.:..||:|||||.||||.|||.||.|||:|||||||||.:...|.:||.
Mosquito   442 FLLSKLSITMSFGTLYIYTVEIFPTNLRQSLLSTCSMFGRIGSMIAPQTPLLAKVWTPLPMILFG 506

  Fly   517 GAAIVSGLLTLFFPETTNVVLPTTVQEA 544
            ...|.|.:.:|.||||.|..||.|::||
Mosquito   507 CLGISSAITSLQFPETLNNELPNTLEEA 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	180/401 (45%)
LOC1280331	XP_061517658.1	None