Protein Alignment SLC22A and LOC1277194

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_316638.4
• Gene: LOC1277194 / 1277194
• VectorBaseID: AGAMI1_010343
• Length: 720
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 158/587 - (26%)
• Similarity: 256/587 - (43%)
• Gaps: 68/587 - (11%)

  Fly     1 MAASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMF---HAMFSVTY 62
            |.|:.......||...|.      |..|.:|.|:|:|||:|.|:|||: :|..|   ...||..:
Mosquito    83 MVATNGASTGAAVAEKPV------VDFDDLLPHVGEFGRYQKILFLLM-IPFAFFVAFVYFSQIF 140

  Fly    63 VFTAATVTHRC--------SVEE---CDLPGSNYYEPHTNWSIPKNGK---DLDSCNRYT----- 108
            : |.....|.|        ||||   ..:|....|....:..:..:|.   ....|..|.
Mosquito   141 I-TLVPEEHWCYVPELQHLSVEERRALAIPVDESYGAELDAGVVGDGSPPISYSKCTMYAVNFTE 204

  Fly   109 ------NSELPQWNHSVDICSADHFTKNKEACAHN-EFVFRD-DEVTISNDFGIFCDDEWKLSMV 165
                  ....|.|              ..:.|.|. |:.|.| ...|.:.||...||..:..::.
Mosquito   205 VLANNIRKADPSW--------------PTQPCRHGWEYNFTDVPYQTAATDFEWVCDHAYLPTLA 255

  Fly   166 GTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTL 230
            .:|..||...|..:.|::||||||..::|...::|...||..:|..::..|.:..||........
Mosquito   256 QSIFFLGAIVGGLLFGWIADRYGRIPALAGCNLIGFAAGVATAFVGNFWQFSLCRFLVGFAFDNC 320

  Fly   231 YSTCFVIGIELVGPKRRVLACSV-ITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW 294
            ::..:::.:|.||||.|....:: |.:|:......|...|....||:....:|..|..:.:....
Mosquito   321 FTMMYILVLEYVGPKWRTFVANMSIALFFTTASCALPWIAYYLADWKTFAIVTSAPLALAILTPL 385

  Fly   295 ILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVL----DKLVLANRDKLQQSSESRFPIRE 355
            ::|||.|||:||||.::|..||::...:||:.:...|.    |..|   |.:.::::.|.:.:.:
Mosquito   386 VVPESARWLVSQGKIDKAIGILKKFETINKKTIDAKVYQEFSDSCV---RLQEEEAANSNYSVLD 447

  Fly   356 AFKNFKWRIANCSL----CWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDR 416
            .||.  .|:.|.::    .|:...||:.|...||..|..|.:..|...|..|:|......|.:||
Mosquito   448 LFKT--PRLRNITILLIVIWMAISLVFDGHVRNVGSLGLDLFFTFTVAAATELPADTFLTLTLDR 510

  Fly   417 FGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNS 481
            :|||:..||.|:||||  .....|..........|.::|:.::..|:.:...:|:|:.||.:|..
Mosquito   511 WGRRWLACGTMVASGL--FSLFATMVPMGAYSATLAILGRFSVNISYNIGLQYAAELLPTVVRAQ 573

  Fly   482 LLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADA 546
            .::|..:||...|::||....||....:.|.::.....|..|||:|..|||....||.|:.:.:.
Mosquito   574 GVAFIHIMGYVASIVAPFVVYLANISPSLPLIVLGILGIFGGLLSLLLPETLGHDLPQTLADGEE 638

  Fly   547 IG 548
            .|
Mosquito   639 FG 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	114/404 (28%)
LOC1277194	XP_316638.4	2A0119	111..632	CDD:273328	147/543 (27%)