Protein Alignment SLC22A and LOC1276213

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_315530.5
• Gene: LOC1276213 / 1276213
• VectorBaseID: AGAMI1_005555
• Length: 569
• Species: Anopheles gambiae
• Alignment Length: 557
• Identity: 157/557 - (28%)
• Similarity: 260/557 - (46%)
• Gaps: 49/557 - (8%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMF-SVTYVFTAATVTHRCSVEECDLPGSNYYEPHTN 91
            |:||.....||.:|.||..::..|..|...| :.:.:|.||...|.|.|.:.|...:::.:...|
Mosquito     4 DSILDMCDGFGAYQKIIIGVLLFPATFPCAFHAYSQLFLAAKPNHWCKVPQFDGFDNHFTDLLKN 68

  Fly    92 WSIPK-----NGKDLDSCNRYTN--SELPQ------WNHSVDICSADH-FTKNKEACAHNEFVFR 142
            .|||:     .......|:.|..  ||:..      .|.|::..|..: .|..:...::::.:|.
Mosquito    69 ISIPQLPYSDGTTGYSKCSMYLRNYSEITSHLRSAAGNVSLEQLSPPNGITSCRHGWSYDQSIFN 133

  Fly   143 DDEVTISNDFGIFCDDEWK-------LSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILG 200
            .   |:..|:.:.||.::.       ..:.|.|.|||       .|::.|.:||..|..|..::.
Mosquito   134 S---TVVTDWNLVCDRDFDTTTALMVFGVAGLIGNLG-------FGYMQDYWGRKLSFFLCLVVQ 188

  Fly   201 AVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLL 265
            ...|.:.:...|||.:||...:..:|...:.|:.:::.||||.||||.....:..:.|:||.|||
Mosquito   189 VTAGAVGAAMWSYGSWLVTRIVVGLTVPAILSSPYMLAIELVEPKRRNFCTIISNIAYSVGLVLL 253

  Fly   266 AMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPE- 329
            ::......|||.|......|.|:|..::.::|||.|||.::||..:|:.||.:.|.||.:.:.:
Mosquito   254 SVIVYYERDWRSLSIAVSLPLLVLFLFYTLIPESPRWLAARGKYSQAQRILLKMARVNGKTIDDG 318

  Fly   330 --SVLDKLVLA----------NRDKLQQSSESRFPIREAF--KNFKWRIANCSLCWIVHVLVYYG 380
              .:||:.:.|          ..|:...|......:|..|  ...:.:....:..|:.:..||.|
Mosquito   319 YRKLLDERIKALSLEDAPEHPATDETANSHAHEIGLRHLFDKPQMRRKTTFVAFIWLTNTSVYVG 383

  Fly   381 LSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQP 445
            ||.....|.||:..||....|||:|.:.:....::.||||..|...|:..||.|..||.  ....
Mosquito   384 LSYYAPALGGDEIFNFFLAGLVELPTYIVLWPSLNLFGRRGVLFTTMVIGGLACAFTII--PQGR 446

  Fly   446 VLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANA 510
            ...|:|:.:||:.::::|.|:...|||||||.:|...:||||::|..|.::.|......|.....
Mosquito   447 TTTLILYCIGKMGVSSAFVVVPLTASEIYPTVIRGLGMSFCSVVGMLGPIVIPLMNYTGKENVAI 511

  Fly   511 PAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAI 547
            |.::...|....|:.:||.|||.|:.||.|:.:.:.|
Mosquito   512 PLVIMGLALTAGGIASLFLPETKNMPLPQTLADGEKI 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	119/415 (29%)
LOC1276213	XP_315530.5	None