Protein Alignment SLC22A and LOC1275246

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_061510474.1
• Gene: LOC1275246 / 1275246
• VectorBaseID: AGAMI1_008850
• Length: 557
• Species: Anopheles gambiae
• Alignment Length: 546
• Identity: 165/546 - (30%)
• Similarity: 264/546 - (48%)
• Gaps: 47/546 - (8%)

  Fly    24 DVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECD--------- 79
            |..|:.::..||.|||:|...|:|..|..:...:..::.|..||...|||.:|..|
Mosquito     4 DQKLEELMGLLGDFGRYQAFQFVLHLLAAVTAGLHMLSLVTVAAVPEHRCFIEALDSASATSNGT 68

  Fly    80 -LPGSNYYEPHTNWSIPKNGK-DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFR 142
             ||..:....:    ||.|.. :|:||..|            |..:||:.|  ..:|  :.:|:.
Mosquito    69 ILPSFSQLASY----IPLNADGELESCLMY------------DPLAADNGT--TVSC--SSYVYN 113

  Fly   143 DDEVTISN--DFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGV 205
            :.....|.  ::.:.||..|..::..||..||.|.|....|.:||:.||........::..:|||
Mosquito   114 NTYYQSSRTIEWNLVCDKRWMGALGQTIYMLGVFTGAVWLGGLADKIGRKKVFCWSALMQLILGV 178

  Fly   206 IRSFSPSYGWFLVFEFLDNMTSST-LYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSA 269
            ..:|:|.:..|||..:|..:..|. .|.|.||:.:|||||.:|. .|.:.......|.::|..:.
Mosquito   179 AVAFTPEFISFLVLRYLYGIFGSAGSYITGFVLTMELVGPSKRT-PCGISFQGAFAGGIMLVAAW 242

  Fly   270 KAFHDWRILLRITYG-PSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLD 333
            .|....|::|::.|| ..|:|:|::||:.||.|||..||::..|.||:.||..:|.|.:.   :|
Mosquito   243 GALIPDRMILQVVYGLHGLLLVAHWWIMDESPRWLWMQGRKREAVNIVDRAVRMNGRGMN---VD 304

  Fly   334 KLVLANRDK---LQQSSESRFPIREAFK--NFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKY 393
            |......||   .:::|.:...:.:.||  |.:....|..|||..:.:.||||||:...|.|:.:
Mosquito   305 KEYYLVEDKTAYTEEASATSAGLADLFKTPNLRKMTLNVCLCWFANSITYYGLSLSAGKLSGNPF 369

  Fly   394 NNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCI-GTIFTGADQPVLQLVLFLVGKL 457
            .....:.|||.|.:.....::|:.|||.....||:..|:||| ....|........:|:|  |||
Mosquito   370 LILFLMGLVEFPSYISISYLLDKLGRRSITSSLMIVGGICCIVAAYLTRGSTESTSIVMF--GKL 432

  Fly   458 TITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVS 522
            .|..||.|:|.:::|::||.:|||.:...||..|....:.|...||..:....||::|...:::|
Mosquito   433 FIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLAGAMTPMITLLDSFDPKIPAVIFGVISLIS 497

  Fly   523 GLLTLFFPETTNVVLPTTVQEADAIG 548
            |...||.|||....:|.::.:.:..|
Mosquito   498 GTWVLFLPETMGKPMPQSLMDGENFG 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	127/403 (32%)
LOC1275246	XP_061510474.1	None