Protein Alignment SLC22A and LOC1273930

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_003436715.2
• Gene: LOC1273930 / 1273930
• VectorBaseID: AGAMI1_008511
• Length: 588
• Species: Anopheles gambiae
• Alignment Length: 582
• Identity: 150/582 - (25%)
• Similarity: 247/582 - (42%)
• Gaps: 101/582 - (17%)

  Fly    21 DSEDVTLDAILKHLGQFGRFQ-----LIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSV---EE 77
            |:.|.:.|.|:...|..|:||     |..|..||    |.:|..::.:.......|.|.|   |:
Mosquito     2 DTPDDSYDEIMAQAGNDGKFQRRYNLLFNFGAIC----FASMSYMSIILALNKPPHNCFVPGMEQ 62

  Fly    78 CDLPGSNYYEPHTNWSIPKNGKD-----LDSCNRYTNSE------LPQWNH-SVDICSADHFTKN 130
            .::..:|.::   |.::|:...:     ...|..|..:|      ..:|:. |.||..
Mosquito    63 YNITDANLWK---NLTLPRETDNRGQLGYSKCQMYNITEQHLQRHYSEWSFASSDIID------- 117

  Fly   131 KEACAHNEFVFRD--DEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSI 193
               ||:.....|.  |...|: ::...||..::.:.:...|.||:.||..|.|.:.|..||....
Mosquito   118 ---CAYGYEYDRTYYDRTPIT-EYDWICDKGFRETNIFIYNRLGELFGTVIFGHLGDTLGRRPVF 178

  Fly   194 ALGGILGAVLGVIRSFSPSYGWFLVF---EFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVIT 255
            .|..::..|..::..|:.:|  ::||   ..:.::|:.:::....:|.:|:...:||.....:..
Mosquito   179 YLSILIITVGRLVSMFTAAY--YVVFCIAAVVGSLTAHSIFQAPLIIAMEISKSERRGHISMMQC 241

  Fly   256 VFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILP----ESVRWLLSQGKEERAKNIL 316
            :.:..|..:|.|...|..||...|.|...|    :..|..:|    ||.|||.::|....|....
Mosquito   242 IGWTTGLCILPMVFWATKDWFWALLIVTMP----IVLFMFIPSYTIESPRWLATRGNYREAMVQF 302

  Fly   317 RRAAHVNK-REL--PESVLDKLVLANR-DKLQQSSESRFPIREAFKNFKWRIANCS----LCWIV 373
            |:.|.:|. |||  .|.||:|.:..:| ||:       :.:...|..  ||:|..:    |||.|
Mosquito   303 RKIATINGIRELAFDERVLEKRLANHRTDKV-------YGLASLFNG--WRMAKNTMLVILCWTV 358

  Fly   374 HVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTI 438
            ..:.|:.|.|....:||:.:.||.|..|:|:|..|......||||||.:     .|..|||...:
Mosquito   359 CSVTYFTLVLLSSRMDGNPFLNFMYQGLIEVPAAFAGQRAADRFGRRAT-----NAMALCCATAV 418

  Fly   439 FTGADQPVLQLVLFLVGK----------LTITASFQV-LYFF-----ASEIYPTNLRNSLLSFCS 487
            .         |||.|:.:          ||....|.: :.||     :.|||||.||.:.::..:
Mosquito   419 C---------LVLVLIVRDPANEMAATVLTTFVKFCISITFFGVNLQSIEIYPTCLRQTGMAVGT 474

  Fly   488 MMGRFGSMLAPQTPLL-AKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548
            :......::.|....| .:|....|.::...::.|..|..||.|||.:..||.|::||...|
Mosquito   475 IAATIFGIVGPYVVHLGTEYDVRYPFLVMGLSSAVGILAALFLPETLHQSLPNTIEEAQKFG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	111/427 (26%)
LOC1273930	XP_003436715.2	None