Protein Alignment SLC22A and LOC1272915

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_311838.5
• Gene: LOC1272915 / 1272915
• VectorBaseID: AGAMI1_005250
• Length: 696
• Species: Anopheles gambiae
• Alignment Length: 560
• Identity: 138/560 - (24%)
• Similarity: 236/560 - (42%)
• Gaps: 58/560 - (10%)

  Fly     2 AASEAPPA----DPAVE--------VAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICL---P 51
            |||.:.|.    ||:.:        ::..|.|.:.   |.|.:::|.:||:|.....|:||   |
Mosquito    87 AASNSAPCGKVHDPSFDDKSDNSSNLSATANDEDS---DIISEYIGHYGRWQFGWTFLLCLFQIP 148

  Fly    52 MMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTNWSIP----KNGKDLDSCNRYTNSEL 112
            ..|| :|.:  ||.||.....|:            .|....:||    :|.....:.::.:....
Mosquito   149 TTFH-IFCL--VFQAAQRDFWCA------------RPDHLAAIPLELWRNLTQTATASQCSVRAA 198

  Fly   113 PQWNHSVDICSADHFTKNKEACAHNEFVFR-------DDEV---TISNDFGIFCDDEWKLSMVGT 167
            |..:.:|| ...|||.:.....:..|....       ||.|   ||..:||:.||....:|:|..
Mosquito   199 PYEHLTVD-SILDHFQRAASNASEGELEMACSSGYEYDDTVYGQTIIAEFGLVCDRAHLMSIVEM 262

  Fly   168 INNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYS 232
            ....|...|....|:::|::||..::....:|..|.|....|..|...::....:....|.::..
Mosquito   263 CFLAGAALGSVGSGWISDQFGRRHTLMGFALLQGVTGFALGFVTSLELYMALRVVIGFASMSVAV 327

  Fly   233 TCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRIL-LRITYGPSLILLAYFWIL 296
            ..||:.:|||..:.|.:...:..:..|:..:|.|..|....|||.: ..||....|::.:::| .
Mosquito   328 VSFVLVVELVSGRYRTIIGILNILPVALAYILAAGIAYVARDWRTMQFAITLPGLLLVTSWYW-C 391

  Fly   297 PESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFK 361
            |||.||||::|:.:....:|.|||..|..:||.:....|.....|......|:...:.:.|:.
Mosquito   392 PESPRWLLAKGRLDELCRLLERAASTNHLQLPANYRKALQAEGEDANGGQPEAAISVGDVFRR-- 454

  Fly   362 WRIANCSL----CWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYS 422
             :....:|    .|...:|:|:|::|::..|.||.|.|......||.....:.::::.:.|.|.:
Mosquito   455 -KFIRTTLVMIVVWFGIILIYFGITLHLSNLGGDIYLNTVIAGSVEAIAICLSIVVVLKLGLRIN 518

  Fly   423 LCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCS 487
            |...|:.:||.||...|.......|.:.|.:|.|..:.|...::..|.:..|||.:||..:...:
Mosquito   519 LFLYMVVAGLSCIVMNFVPDGNLWLIITLAMVVKCCVGACNAIIPTFTAYQYPTTMRNLGVGVGN 583

  Fly   488 MMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTL 527
            .......::.|...||.......| |...|...:.|.|:|
Mosquito   584 FAAGVALIIVPYLWLLEHVDQYLP-MTIMGVFSIVGALSL 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	102/407 (25%)
LOC1272915	XP_311838.5	MFS_SLC22	231..620	CDD:340875	99/393 (25%)