Protein Alignment SLC22A and LOC1271055

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_061512323.1
• Gene: LOC1271055 / 1271055
• VectorBaseID: AGAMI1_001179
• Length: 596
• Species: Anopheles gambiae
• Alignment Length: 627
• Identity: 144/627 - (22%)
• Similarity: 219/627 - (34%)
• Gaps: 215/627 - (34%)

  Fly    10 DPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCS 74
            ||...|||...|.|...      .|..:|||..|: |.||      .:.|.:
Mosquito    85 DPERGVAPIKADFEQAI------ELTGYGRFHYIL-LAIC------GLVSTS------------- 123

  Fly    75 VEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEF 139
             ||.|:...::.       :|....|||     .|::...|.:|:
Mosquito   124 -EEMDVISMSFI-------LPSAQCDLD-----LNTQSKGWLNSI-------------------- 155

  Fly   140 VFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLG 204
                          ||               :|..||..|.|.|||..||...:.:..|:.|...
Mosquito   156 --------------IF---------------IGMMFGAYIWGSVADSLGRKKVLIVISIMNAFCI 191

  Fly   205 VIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVG-------------PK-RRVLACSVIT 255
            |..|||.:|..|:||.||:              |:.|.|             || :|....|.:.
Mosquito   192 VASSFSQTYEVFMVFRFLN--------------GVALGGSGPVIWPYFAEFQPKSKRGSMLSFMA 242

  Fly   256 VFYAVGEVLLA--------------MSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQ 306
            .|:.:|.:|:|              ..|..::.|||.|.:...||.|:.|....||||.::||||
Mosquito   243 AFWTIGNLLVAGLAWLIIPTGIGITTPAFTYNSWRIFLLVCSIPSFIVAALLLYLPESPKFLLSQ 307

  Fly   307 GKEERAKNILRRAAHVN----KRELP--ESVLDKLVLANRDKLQQSSESRFPIREAFKN------ 359
            ||.:.|..|.|.....|    |.:.|  |.::|:.:   |::|:..::   ||:..:|.
Mosquito   308 GKIDEALAIFRGIYVTNTGKSKDQYPVRELLIDECL---REELEAVTK---PIKNKYKRMLYDIL 366

  Fly   360 -----------FKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNF----------------- 396
                       .|:.|.:.::.:..|: .||||    ::...:.:|.|
Mosquito   367 DNSKQVFMSPILKFTIISITINFTFHI-GYYGL----MMWFPELFNRFDEFTRAHPGVEDASVCQ 426

  Fly   397 -------------AYIALVEIPG-FFMPLLI---------------MDRFGRRYSLCGLMLASGL 432
                         ..:....||. .||..||               |||.||::.|....:|:|.
Mosquito   427 VTDYVVGMGSHSQTGVCSATIPSTVFMESLITVAAALPANVIAVLGMDRLGRKFFLVFSTMAAGA 491

  Fly   433 CCIGTIFTGADQPVLQLVLFLVGKLTI-TASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSML 496
            |.....|.......|.:.....|.::: .||...|   .:|::|||||.:.::...:..|.|.::
Mosquito   492 CSASMYFVTNQHQNLAVSAIFSGVISMGNASLDCL---ITEVFPTNLRATGVAISMVAARLGGII 553

  Fly   497 APQT-PLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVL 537
            .... ..|...|..||..:.|......||:.||.|.||...|
Mosquito   554 GNVVIATLLDLYCPAPTFIVAVLLAGGGLMCLFLPNTTRTAL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	114/492 (23%)
LOC1271055	XP_061512323.1	None