Protein Alignment SLC22A and Slc22a7

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_659105.2
• Gene: Slc22a7 / 108114
• MGIID: 1859559
• Length: 540
• Species: Mus musculus
• Alignment Length: 549
• Identity: 147/549 - (26%)
• Similarity: 246/549 - (44%)
• Gaps: 31/549 - (5%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGS-NYYEPHTN 91
            :.:|..:|.||.|||...:|:.||.....|..:..:|.||...|.|::.  |.|.: ::.:....
Mouse     4 EELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALP--DAPANLSHQDLWLK 66

  Fly    92 WSIPK-NGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEA------CAHN-EFVFRDDEVTI 148
            ..:|: ......||.|:.   .||...:|.:.:..:.:...|.      |:.. |:...:...||
Mouse    67 THLPRETDGSFSSCLRFA---YPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTI 128

  Fly   149 SNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSY 213
            :.::.:.|.......:..|...:|...|..:.|:::||:||...:.:..:....||::.:.|.:|
Mouse   129 ATEWDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNY 193

  Fly   214 GWFLVFEFLDNMTSSTLYS-TCFVIGIEL--VGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDW 275
            ..|:....|   |.|.|.. |..|:.:||  :..:.|.:|..:.|.|:..|.:||.:.......|
Mouse   194 IMFVTTRML---TGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSW 255

  Fly   276 RILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANR 340
            |.||.....|.:..:...|.:|||.||||:||:.|.||..|...|.:|.|.:.|..|.:..| |:
Mouse   256 RWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEAL-NK 319

  Fly   341 DKLQQSSESRFPIREAFKNFKWRIAN--CSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVE 403
            ....:....|....:.|:..:.|..:  |.:.|......||||:|:...|....|........||
Mouse   320 VITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVE 384

  Fly   404 IPG----FFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQ 464
            :|.    ||:..|:    |||.:..|::||:.|....::...:|.......|.::||....|:|.
Mouse   385 VPSKITVFFLVRLV----GRRLTEAGMLLATALTFGISLLVSSDTKSWITALVVIGKAFSEAAFT 445

  Fly   465 VLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFF 529
            ..|.|.||:|||.||.:.:.|.:::||.|:.|||...||...:...|.:.:.|.:.::....|..
Mouse   446 TAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLLL 510

  Fly   530 PETTNVVLPTTVQEADAIGVKKQSKSKDL 558
            |||....||.|:|:.:..|.|......:|
Mouse   511 PETKKAQLPETIQDVERKGRKIDRSGTEL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	110/403 (27%)
Slc22a7	NP_659105.2	2A0119	11..521	CDD:273328	141/522 (27%)