Protein Alignment SLC22A and LOC101884074

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_073791788.1
• Gene: LOC101884074 / 101884074
• -ID: -
• Length: 725
• Species: Danio rerio
• Alignment Length: 694
• Identity: 128/694 - (18%)
• Similarity: 216/694 - (31%)
• Gaps: 274/694 - (39%)

  Fly    21 DSEDVT--LDAILKHLGQFGRFQLIIFLLICLPMMFHA--MFSVTYVFTAATVTHRCSVEECDLP 81
            |.|::.  .:.|::..|. ||||..:|.::.|.:|...  :|.|.:|..:|
Zfish   128 DEEELAQQYELIIQECGH-GRFQWQLFFVLGLALMSDGVEVFVVGFVLPSA-------------- 177

  Fly    82 GSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEV 146
                   .|:..:|.:|..
Zfish   178 -------ETDMCVPNSGAG---------------------------------------------- 189

  Fly   147 TISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSP 211
                         |    :|::..||...|....|.::|:.||...:.:...:......:.||..
Zfish   190 -------------W----LGSVVYLGMMVGAFFWGGLSDKVGRRQCLLVCMSVNGFFAFLSSFVQ 237

  Fly   212 SYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAM--------- 267
            .|..||....|............|....|.:..::|....|.:.:|:.||.:..:.
Zfish   238 GYSTFLFCRMLSGFGIGGAVPIVFSYFAEFLAREKRGEHLSWLCMFWMVGGIYASAMAWAIIPHY 302

  Fly   268 -------SAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKR 325
                   ||..||.||:.:.:...|.:..:.....:|||.|:.|..||.:.|..:|::....|.|
Zfish   303 GWSFSMGSAYQFHSWRVFVVVCAFPCVSAVVALTFMPESPRFYLEMGKHDEAWMVLKQIHDTNMR 367

  Fly   326 ELPESVLDKLVLANRDKL--------QQSSESRFPIREAFKNFKWRIANCSL----CW------- 371
            ...|.  :|:...||.|:        :..|||..|:.:.....|..:....|    ||
Zfish   368 ARGEP--EKVFTVNRIKIPKQLDELVEMQSESTNPVLKVLFRIKSELHGIWLTFLKCWDYPIKDN 430

  Fly   372 IVHVLV--------YYGLSL--------------------------------------------- 383
            .|.:.:        |||||:
Zfish   431 TVKLAIVWFSLSFGYYGLSVWFPDVIKHLQADEYASRVKIHTSEKIEDFTFNFTLENQIHRNGLF 495

  Fly   384 ------------------------------------NVVLLDGDKYN----------------NF 396
                                                |..:::...||                :|
Zfish   496 INDRFIGMKFKSVTFIDSTFQSCYFEDVSSVGSYFKNCTIIEAFFYNTDIDDSKLVGSSVINSSF 560

  Fly   397 A-------------YIA-----------LVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGT 437
            |             |.|           |..:||..:..|:||:.||...|.|.|:.||:.|. .
Zfish   561 AHNKTGCQMTFDDDYSAYWVYFINFLGTLAVLPGNIVSALLMDKVGRLSMLGGSMVLSGISCF-F 624

  Fly   438 IFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGR---------FG 493
            ::.|..:.::..:|.|...|:|:| :..|....:|:||||.|.:...||:.|.:         ||
Zfish   625 LWFGTSESMMIAMLCLYNGLSISA-WNSLDVVTAELYPTNRRGTGFGFCNAMCKLAAVLGNLIFG 688

  Fly   494 SMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVL 537
            |::.     ::|   :.|.:|.:...:..||:.|..|:|.|.||
Zfish   689 SLVG-----ISK---SIPILLASSVLVAGGLVGLRLPDTRNNVL 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	105/566 (19%)
LOC101884074	XP_073791788.1	None