Protein Alignment SLC22A and LOC100490946

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_031756488.1
• Gene: LOC100490946 / 100490946
• XenbaseID: XB-GENE-29080455
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 128/543 - (23%)
• Similarity: 230/543 - (42%)
• Gaps: 69/543 - (12%)

  Fly    37 FGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTNWSIPKNGKDL 101
            |..||.|:..|:..|:.|....:...||.||...:.|               .:|.::.:.....
 Frog    14 FSPFQAIMVTLLSAPLCFVGTHNFMPVFAAAVPPYNC---------------RSNMTMDQPRYPE 63

  Fly   102 DSCNRY----TNSELP-----QWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISNDFGIFCD 157
            |.|.:|    :||..|     :::||:       ||.                 ||.:::.:.||
 Frog    64 DPCTQYVSSLSNSTKPCEEGWEYDHSI-------FTS-----------------TIISEWDLVCD 104

  Fly   158 DEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFL 222
            .:....:..::...|...|..:.|.:|||:||...|....:..|.:|:..:.||:...:.:|.||
 Frog   105 RQTLKEVAQSVYMAGVLVGAAVYGALADRFGRRAMILCSLLQIAGMGIGVALSPNIIVYCLFRFL 169

  Fly   223 DNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSL 287
            ..|....|......:.:|....:.|.:...:.......|.::|...|.|...||.|......|..
 Frog   170 TGMGICGLIINDLGLAMEWTPRRYRPIVSMIQGYGLTCGAIILVGLAYAIRGWRWLQLTASLPYF 234

  Fly   288 ILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVN-KRELPESVLDKLVLANRDKLQQSSESRF 351
            |.......:|||.|||..:....:|...|.|.|.:| ::|.....|:.|.|.::...:..:....
 Frog   235 IFFLLMCWVPESARWLSLKKHSNQALANLNRVAKINGRKEGGPITLEMLKLDDQHSTKAMTTKLT 299

  Fly   352 PIREAFKNFKWRIAN--CSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIM 414
            |: :.|:....|...  .||.|......::.::|:|     |::....|:......|..:|:.|:
 Frog   300 PL-DLFRTPTMRTITLILSLSWFSSSFGFFAIALDV-----DRFGLSLYLTQGVFAGSELPIRIL 358

  Fly   415 DR-----FGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIY 474
            ..     .|||.::..|::.:|...:.|:....|..:||::|.::.|.::.:.....|.:.:|:|
 Frog   359 ATITAFYIGRRLTISFLLIFAGTLLLCTMAVPKDMLLLQMILTVLAKASLGSCIVCSYLYTAEVY 423

  Fly   475 PTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPT 539
            ||.||.:.|.|.:||.|.|::::|...:...|.:..|.::||...|:|||..|..|||.|..|..
 Frog   424 PTVLRQTGLGFTNMMMRLGAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILLLPETLNCPLMD 488

  Fly   540 TVQEADAIGVKKQSKSKDLDLVV 562
            ||:|.       :|::::|:..:
 Frog   489 TVEEV-------ESRNRELNFQI 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	95/401 (24%)
LOC100490946	XP_031756488.1	2A0119	14..489	CDD:273328	123/519 (24%)