Protein Alignment SLC22A and slc22a31

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_012817743.1
• Gene: slc22a31 / 100485676
• XenbaseID: XB-GENE-6048942
• Length: 558
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 126/554 - (22%)
• Similarity: 211/554 - (38%)
• Gaps: 111/554 - (20%)

  Fly    34 LGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRC---SVEECDLPGSNYYEPHTN---- 91
            :|.|||:..::.....||.:..||...:.:...|..:::|   |.:.|  ||::.:|..:|
 Frog    11 VGGFGRYTRLLAAATWLPNVALAMGFFSELMYTAVPSYQCQGVSGDPC--PGNSSWENSSNQSQH 73

  Fly    92 ----WSIPKNGKDLDSCNRYTNSEL-PQWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISND 151
                |.....|        :.||.: .||.
 Frog    74 CPGGWHFQAQG--------WLNSNIVTQWE----------------------------------- 95

  Fly   152 FGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWF 216
              :.||.:||:.:......:|...|..|.|.:.||.||..:.....::...|||..:|:.||..|
 Frog    96 --LLCDRQWKVPLEKISYLVGWLLGYIIFGCICDRLGRRAAFIGALVMALPLGVAVTFTSSYFSF 158

  Fly   217 LVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRI 281
            |..........:.::.:.::..:||..|.:|::...:...|:..||:||...|....|||:|...
 Frog   159 LPLRAGFGAALAGMFLSFYISRVELCSPSQRLMVTMIGGFFWVAGELLLPGMAVLCSDWRVLQGS 223

  Fly   282 TYGPSLILLAYFW----ILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDK-LVLANRD 341
            ..| :|:||..:|    :.|||.||||:..:.|:.|:.|...|..|...:.|....: .|....|
 Frog   224 ITG-TLMLLGVYWCGHTLYPESPRWLLATQQVEQCKSELHMFARANGINIGEDASGQDHVFTEID 287

  Fly   342 KLQQSSESRFPIREAFK-------NFKWRIA---------NCSL--CWIVHVLVYYGLSLNVVLL 388
            .|.:.    ||..:.:.       ...||.|         .|.:  |:..::.| :|..:...|.
 Frog   288 SLCEG----FPRPQYYSICSIFGTRLIWRNALILGFTAFIGCGIRPCFARNLQV-FGPYIPYFLQ 347

  Fly   389 DGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTI-FTGADQPV-LQLVL 451
            .|.           ||....:..:.:...|||..|....:.:|.|.:..: .|..|..: ..:|:
 Frog   348 AGS-----------EIVACILICICVSHCGRRSVLLLFTILTGFCSLLLLALTQLDLFIEASIVI 401

  Fly   452 FLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAK-----YYANAP 511
            .:||.|...|...:..|:|.|:.||.:|.|.|.....:...|....|...|..|     |:
 Frog   402 SVVGSLCSHAVVMLSVFYACEVLPTVIRGSGLGLIMGINMLGRASLPFIELQHKSGYFLYH---- 462

  Fly   512 AMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEAD 545
             ::.:...|:|.|..|..|||....||.|::..:
 Frog   463 -VVLSSFCILSVLSLLLLPETKRKSLPETLRHGE 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	98/423 (23%)
slc22a31	XP_012817743.1	MFS_SLC22A31	67..470	CDD:341001	101/469 (22%)