Protein Alignment SLC22A and slc22a7b.4

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_073784582.1
• Gene: slc22a7b.4 / 100000058
• ZFINID: ZDB-GENE-170717-1
• Length: 550
• Species: Danio rerio
• Alignment Length: 571
• Identity: 149/571 - (26%)
• Similarity: 251/571 - (43%)
• Gaps: 54/571 - (9%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTNW 92
            |.||.....|||:|:.:.:|:.:|.:......:...|.||..:|.|.:...|..|..........
Zfish     4 DNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSHHCDISSLDADGLGNLTQKERL 68

  Fly    93 --SIP--KNGKDLDSCNRYTNSELPQWNHSVDICSAD-----------HFTKNKEACAHNEFVFR 142
              |:|  ::|... ||:.:.:   ||:...::..|:.           ||.       ::.|:
Zfish    69 IVSVPAQEDGTPA-SCHMFAH---PQFQLLINSSSSSALPVVECQNGWHFD-------NSTFI-- 120

  Fly   143 DDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIR 207
               .|::..|.:.||.........||..:|...|....|.:.|:|||...:.:..:...|..|..
Zfish   121 ---STLATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTS 182

  Fly   208 SFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAF 272
            :||.||..|..|.||..:..:.:.:...|:.||.|..|.|.......::.:::|.:|||..|...
Zfish   183 AFSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNMLLAGFAFMV 247

  Fly   273 HDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNK------RELPESV 331
            .|||:|:.|...|..:..|.:|.:|:|.|||::.||.|.|...|.:.|..||      |..||::
Zfish   248 TDWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRLDFTSRVKPETL 312

  Fly   332 LDKLVLANRDKLQQSSESRFPIREAFKNFKWRIAN--CSLCWIVHVLVYYGLSLNVVLLDGDKY- 393
            ...:.:.:|.       ..:...:..|..:.|...  ..:.|......|||:|||:.....|.|
Zfish   313 STVVTVDHRG-------HSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNITGFGLDPYL 370

  Fly   394 NNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLT 458
            .:|.| |.:|:|...:....:::.|||.:..|.::.:|.|.:..|.|..:....:.|:.::||..
Zfish   371 THFIY-AAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTFRTVIAVLGKGL 434

  Fly   459 ITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSG 523
            ..|||..:..:.:|:|||.:|.:.|.|.:.|.|.|:.::|...||...:...|.::|...||..|
Zfish   435 SEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLLPEVIFCSMAIFCG 499

  Fly   524 LLTLFFPETTNVVLPTTVQEADAIGVK------KQSKSKDLDLVVTATQAQ 568
            ::.|..|||.|..||.||::.:.:..|      ....:..|.|.:||...|
Zfish   500 IIALLLPETNNASLPETVEDIEDMRKKPVYFTTADQSAMPLKLPLTADTTQ 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	109/402 (27%)
slc22a7b.4	XP_073784582.1	None