DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mub and HEN4

DIOPT Version :9

Sequence 1:	NP_001246875.1	Gene:	mub / 40436	FlyBaseID:	FBgn0262737	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001190612.1	Gene:	HEN4 / 836560	AraportID:	AT5G64390	Length:	866	Species:	Arabidopsis thaliana

Alignment Length:	453	Identity:	105/453 - (23%)
Similarity:	179/453 - (39%)	Gaps:	120/453 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TSSSAGGASIKHEDPSVT------LTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISD--G 62
            ||:|....:.....||..      :..:::...:..|.:||..|::|.....|:||.||:.:  .
plant   428 TSASMANTATMKPPPSEVEVGNQDVVFKILCSTENAGGVIGTGGKVVRMLHSETGAFINVGNTLD 492

  Fly    63 SCPERIVTVSGTTN-------AIFSAFTLITKKFEEWCSQFNDVGKVGKTQIPIRLIVPASQCGS 120
            .|.||::.|:.:.|       |..:...:.::.||...::..|.|.  ::.|..||:||.||.|.
plant   493 DCEERLIAVTASENPECQSSPAQKAIMLIFSRLFELATNKILDNGP--RSSITARLVVPTSQIGC 555

  Fly   121 LIGKSGSKIKEIRQTTGCSIQVAS-EMLP---NSTERAVTLSGSAEQITQCIYQICLVMLESPPR 181
            ::||.|..:.|:|:|||.:||:.. |..|   :..::.|.::|....:.:.|:.|...:.:|
plant   556 VLGKGGVIVSEMRKTTGAAIQILKVEQNPKCISENDQVVQITGEFPNVREAIFHITSRLRDS--- 617

  Fly   182 GATIPYRPKPQVTGPVILANGQAFTIQGNYAVPTQETCPVF-------PLALATGGLHAGISGLA 239
                            :.:|....::..:.:..|.|.   |       ||::   |.|..:|..|
plant   618 ----------------VFSNSMKNSLAKSSSALTTER---FYDRQSDNPLSI---GSHQSVSNPA 660

  Fly   240 -----------DPLLKGAHLQ-------GAIP------------------AHH------------ 256
                       |..|.|:|..       |..|                  :|:
plant   661 TNSSSLHRRSEDSFLSGSHSSVNYSRSVGTDPYIRPEDPFPDRFNPSAGYSHNFGRRFTMDHSDN 725

  Fly   257 -HHLQQMPD--VAKNPLASLAALGLA--GMNPASTGGINHTANPANRAQQQQH----------EM 306
             |||.:.|.  .|..|.|:...|..|  |::.|..|.:..:.: |.......|          |:
plant   726 SHHLTEAPSRLWASPPPAAPRGLSDASGGLSSARAGHVLGSLH-ARLVFSSGHKSAIVTNTTVEI 789

  Fly   307 TVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVALAQYLIN 369
            .|..:.:..:.|:.|..:.::||||||.:.|   .|...|.:||.|.|||.||....||.|::
plant   790 RVPANAMSFVYGEQGYNLEQLRQISGARVII---HEPPLGTSDRIIVISGTPDQTQAAQNLLH 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	PCBP_like_KH	25..86	CDD:239089	16/69 (23%)
		PCBP_like_KH	109..172	CDD:239089	22/66 (33%)
		KH-I	305..368	CDD:238053	23/62 (37%)
HEN4	NP_001190612.1	PCBP_like_KH	49..102	CDD:239089
		PCBP_like_KH	151..218	CDD:239089
		PCBP_like_KH	453..522	CDD:239089	16/68 (24%)
		PCBP_like_KH	543..611	CDD:239089	22/67 (33%)
		KH-I	786..849	CDD:238053	24/65 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2190
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1137
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.870