DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mub and RCF3

DIOPT Version :9

Sequence 1:	NP_001246875.1	Gene:	mub / 40436	FlyBaseID:	FBgn0262737	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_200118.3	Gene:	RCF3 / 835386	AraportID:	AT5G53060	Length:	652	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	119/550 - (21%)
Similarity:	199/550 - (36%)	Gaps:	149/550 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NNTSSSAGGA-------SIKHEDPSVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISD 61
            ||.....||.       |..|.:...|.|.|::....:.|.:|||.|.|:...|:.:||.||:.:
plant    41 NNRYRGGGGGGGGNGRPSKSHPETMATTTYRILCHDAKAGGVIGKSGTIIKSIRQHTGAWINVHE 105

  Fly    62 ---GSCPERIVTVSG---------------TTNAIFSAFTLITKKFEEWCSQF----------ND 98
               |.. |||:.:|.               ...|:||    :..:..|..:||          .|
plant   106 LVPGDA-ERIIEISDNRRRDPDGRMPSFSPAQEALFS----VHDRILESEAQFGYGGPPPEEEED 165

  Fly    99 VGKV--GKTQIPIRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPNSTE--RAVTLSG 159
            .|.|  |..::..||:|.....|.|:||.|..|:::|..|...|::    ||..:.  |.|:||
plant   166 YGGVRPGGGRVVTRLVVSRMHVGCLLGKGGKIIEQMRIETKTHIRI----LPRESNLPRCVSLS- 225

  Fly   160 SAEQITQCIYQICLV------------------------MLESPPR---GATIPYRPK------- 190
              |:|.|.:.::..|                        ...||.|   .|...|.|:
plant   226 --EEIVQIVGELNAVKNALAIVSSRLRESQHRDRSNFQGRSHSPERSFAAAGDDYMPQLRRQSSD 288

  Fly   191 --PQVTGPVILANGQAFTIQGNY-----AVPTQET-----------CPVFPLALATGGLHAGISG 237
              |:..    ..|....:.|.||     |||..|.           ||...:....|.....|..
plant   289 RFPRGN----FRNNNFSSRQSNYAEEAPAVPVGENVYSEELVFQILCPADKIVRVVGESQGIIDL 349

  Fly   238 LADPLLKGAHLQGAIPAHHHHL-----QQMPDVAKNPLASLAALGLAGMNPASTGGINHTANPAN 297
            |.:.:.....:...:......:     ::.||   :|..           ||....::......:
plant   350 LQNEIGVDVRVSDPVAGSDEQIITISSEEAPD---DPFF-----------PAQEALLHIQTQIID 400

  Fly   298 RAQQQQHEMTV-----SNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEE--REGGNTDRTITIS 355
            ....:.:.:|.     |.|.| |:.||.|: ::||.:::|..::|...||  |.....|..|.|:
plant   401 LIPDKDNLITTRLLVPSRDSI-CLEGKAGS-VSEISRLTGTSVQILAREEIPRCASINDVVIQIT 463

  Fly   356 GNPDSVALAQYLINMSVELQKANLLEQAQSQQNGGAAAAPGAAAAGVAAVTGAAA---------- 410
            |  :..|..:.|:.::: |.::::.::...::...|:.:......|||.|...|:
plant   464 G--EIRAAREALVELTL-LLRSHMFKELSQKETPPASTSTTGPLEGVAGVMEVASSNNTIQSREG 525

  Fly   411 PTSATNGAITTVTLTSGTGVVGAGAAGAAG 440
            ||| :|..:..|:........|.|:...||
plant   526 PTS-SNLNLQQVSTILPQFKEGFGSVAKAG 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	PCBP_like_KH	25..86	CDD:239089	21/78 (27%)
		PCBP_like_KH	109..172	CDD:239089	21/64 (33%)
		KH-I	305..368	CDD:238053	20/69 (29%)
RCF3	NP_200118.3	PCBP_like_KH	69..143	CDD:239089	21/78 (27%)
		PCBP_like_KH	179..246	CDD:239089	22/73 (30%)
		KH-I	326..395	CDD:320758	10/82 (12%)
		KH-I	410..477	CDD:320758	21/70 (30%)
		KH_1	578..641	CDD:306517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2077
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X408
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.920