DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mub and PEP

DIOPT Version :9

Sequence 1:	NP_001246875.1	Gene:	mub / 40436	FlyBaseID:	FBgn0262737	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_194330.1	Gene:	PEP / 828706	AraportID:	AT4G26000	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	121/497 - (24%)
Similarity:	191/497 - (38%)	Gaps:	135/497 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RLIMQGKEVGSIIGKKGEIVNRFREESGAKINISDG--SCPERIVTVSG----------TTNAIF 79
            |:|:...:||:|||:||:.:.:..||:.|:|.:.||  :.|:|||.:||          ..:|:.
plant    77 RMIVPVTKVGAIIGRKGDFIKKMCEETRARIKVLDGPVNTPDRIVLISGKEEPEAYMSPAMDAVL 141

  Fly    80 SAFTLITKKFEEWCSQFNDVGKVGKTQIPIRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVAS 144
            ..|..::...:   :..:||...|.....:||:|.::|..:||||.||.||.|.:.:|.|:::.|
plant   142 RVFRRVSGLPD---NDDDDVQNAGSVFSSVRLLVASTQAINLIGKQGSLIKSIVENSGASVRILS 203

  Fly   145 E----MLPNSTERAVTLSGSAEQITQCIYQICLVMLESPPRGATIPYRPKPQVTGPVILANGQAF 205
            |    ......||.|.|.|.|.:|        |..||:                   |:.:.:.|
plant   204 EEETPFYAAQDERIVDLQGEALKI--------LKALEA-------------------IVGHLRRF 241

  Fly   206 TI--------QGNYAVPTQETCPVFPLALATGGLHAGISGLADP------------LLKGAHLQG 250
            .:        :..|.....:|....|||.:...||...|.|.:|            |.:.:.:..
plant   242 LVDHTVVPLFEKQYLARVSQTRQEEPLAESKSSLHTISSNLMEPDFSLLARREPLFLERDSRVDS 306

  Fly   251 AI-PAHHHHLQQMPDVAKNPLASLAALGLAGMNPASTGGINHTANPANRAQQQQHEMTVSNDLIG 314
            .: |:......|.|     .|::..:.|||.::.|....::.|         .|...:.:.|
plant   307 RVQPSGVSIYSQDP-----VLSARHSPGLARVSSAFVTQVSQT---------MQIPFSYAED--- 354

  Fly   315 CIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDR-TITISGNPDSVALAQYLINMSVELQKAN 378
             |||..|..||.||:.|||.|.|     :|..:.|: |:.|.|....|..|:.||...:...|
plant   355 -IIGVEGANIAYIRRRSGATITI-----KESPHPDQITVEIKGTTSQVQTAEQLIQEFIINHK-- 411

  Fly   379 LLEQAQSQQNGGAAAAPGAAAAGVAAVTGAAAPTSAT-----------------NGAIT-TVTLT 425
               :..|...|.|....|...|....::....|..:|                 .|..| |.|||
plant   412 ---EPVSVSGGYARIDSGYVPAYPPQLSNRQEPLPSTYMGTEPVQYRPTAYSQLGGPSTYTPTLT 473

  Fly   426 SGTGVVGAGAAGAAGVANGANPAANGGGSNGTISATGYASAN 467
            ..|            ..:...||::.|         ||:|.|
plant   474 GQT------------YGSEYRPASDVG---------GYSSYN 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	PCBP_like_KH	25..86	CDD:239089	23/70 (33%)
		PCBP_like_KH	109..172	CDD:239089	24/66 (36%)
		KH-I	305..368	CDD:238053	21/63 (33%)
PEP	NP_194330.1	PCBP_like_KH	75..144	CDD:239089	22/66 (33%)
		PCBP_like_KH	167..235	CDD:239089	27/94 (29%)
		KH_1	343..405	CDD:365809	25/79 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	44	1.000	Domainoid score	I4687
eggNOG	1	0.900	-	-		E1_KOG2190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X408
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870