Protein Alignment mub and NOVA2

DIOPT Version :10

• Sequence 1: NP_001246875.1
• Gene: mub / 40436
• FlyBaseID: FBgn0262737
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_002507.1
• Gene: NOVA2 / 4858
• HGNCID: 7887
• Length: 492
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 120/471 - (25%)
• Similarity: 183/471 - (38%)
• Gaps: 144/471 - (30%)

  Fly    26 IRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISDG-----SCPERIVTVSGTTNAIFSAFTLI 85
            :::::.....||||||.|:.:.:.::|:||.|.:|..     ...||:..|.||..|:.:..:.|
Human    35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFI 99

  Fly    86 TKKFEEWCSQFN--DVGKVGKTQIPI--------RLIVPASQCGSLIGKSGSKIKEIRQTTGCSI 140
            .:|..|......  :|..:.:.|..:        :||||.|..|.:|||.|:.:|.:.:.:|..:
Human   100 AEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWV 164

  Fly   141 QVASEMLP---NSTERAVTLSGSAEQITQCIYQICLVMLESPPRGA--TIPYRPKPQVTGPVILA 200
            |::.:  |   |..||.||:||..||:.:.:..|...:.|.|...:  .|.|   ..|.|||..:
Human   165 QLSQK--PEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISY---ANVAGPVANS 224

  Fly   201 NGQAFTIQGNYAVPTQETCPVFPLALATGGLHAGISGLADPL-LKGAHLQGAIPAHHHHLQQMP- 263
            |...    ..||.|..    |.|.|.|...  |..|||..|. |.|.   ||.||      .:|
Human   225 NPTG----SPYASPAD----VLPAAAAASA--AAASGLLGPAGLAGV---GAFPA------ALPA 270

  Fly   264 ---------DVAKNPLASLA----ALGL---------------AGMNPASTGGINHTANPANRA- 299
                     ..|.|.|||..    :|||               ||.|||:....|..|:.|..|
Human   271 FSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAG 335

  Fly   300 ----------------------------------------------------------------- 299
                                                                             
Human   336 AGPAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKL 400

  Fly   300 ----QQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDS 360
                .::..|:.|..:|:|.|:||||..:.|.::::||.|:||...|...|..:|.:||:|:|.:
Human   401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465

  Fly   361 VALAQYLINMSVELQK 376
            ...|||||:..|..::
Human   466 TQAAQYLISQRVTYEQ 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	KH-I_PCBP_rpt1	26..92	CDD:411866	20/70 (29%)
		KH-I_PCBP_rpt2	107..177	CDD:411806	24/80 (30%)
		KH-I_PCBP_rpt3	301..371	CDD:411867	27/69 (39%)
NOVA2	NP_002507.1	Bipartite nuclear localization signal. /evidence=ECO:0000255	10..26
		KH-I_NOVA_rpt1	33..104	CDD:411863	20/68 (29%)
		KH-I_NOVA_rpt2	131..200	CDD:411864	24/70 (34%)
		KH-I_NOVA_rpt3	409..477	CDD:411807	27/67 (40%)