DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mub and pcbp2

DIOPT Version :9

Sequence 1:	NP_001246875.1	Gene:	mub / 40436	FlyBaseID:	FBgn0262737	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_957486.1	Gene:	pcbp2 / 321844	ZFINID:	ZDB-GENE-030131-563	Length:	318	Species:	Danio rerio

Alignment Length:	350	Identity:	175/350 - (50%)
Similarity:	227/350 - (64%)	Gaps:	56/350 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISDGSCPERIVTVSGTTNAIFSAFTLI 85
            :|||||||:|.|||||||||||||.|.:.||||||:||||:|:|||||:|::|.|.|||.||::|
Zfish    11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTTAIFKAFSMI 75

  Fly    86 TKKFEE-WCSQFNDVGKVGKTQIPIRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPN 149
            .:|.|| ..|..::.....|..:.:|::||||||||||||.|.||||||::||..:|||.:||||
Zfish    76 IEKLEEDISSSMSNSTATSKPPVTLRIVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPN 140

  Fly   150 STERAVTLSGSAEQITQCIYQICLVMLESPPRGATIPYRPKPQVTGPVILANGQAFTIQGNYAVP 214
            |||||:|::|:...|.:|:.|||:|||||||:|.||||||||. ..|||.|.|||:.:||.:|:|
Zfish   141 STERAITIAGTPLSIIECVKQICVVMLESPPKGVTIPYRPKPS-GSPVIFAGGQAYAVQGQHAIP 204

  Fly   215 TQETCPVFPLALATGGLHAGISGLADPLLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLAALGLA 279
            ..:...:..||                                 :||.|    .|||
Zfish   205 QPDLTKLHQLA---------------------------------MQQSP----FPLA-------- 224

  Fly   280 GMNPASTGGINHTANPANRAQQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEERE 344
               |:|.|   .||.....||...||:|:.|||||||||:.|.||.||||:|||.|:|:|..|
Zfish   225 ---PSSQG---FTAGMDASAQTGSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-- 281

  Fly   345 GGNTDRTITISGNPDSVALAQYLIN 369
             |::||.:||:|:|.|::||:||||
Zfish   282 -GSSDRQVTITGSPASISLAEYLIN 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	PCBP_like_KH	25..86	CDD:239089	43/60 (72%)
		PCBP_like_KH	109..172	CDD:239089	39/62 (63%)
		KH-I	305..368	CDD:238053	36/62 (58%)
pcbp2	NP_957486.1	PCBP_like_KH	15..76	CDD:239089	43/60 (72%)
		PCBP_like_KH	99..163	CDD:239089	39/63 (62%)
		KH-I	242..304	CDD:238053	37/64 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574639
Domainoid	1	1.000	97	1.000	Domainoid score	I7176
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2578
OMA	1	1.010	-	-		QHG52907
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001027
OrthoInspector	1	1.000	-	-		otm25231
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1164
SonicParanoid	1	1.000	-	-		X408
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.030