DRSC/TRiP Functional Genomics Resources

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Protein Alignment mub and Igf2bp3

DIOPT Version :9

Sequence 1:NP_001246875.1 Gene:mub / 40436 FlyBaseID:FBgn0262737 Length:573 Species:Drosophila melanogaster
Sequence 2:XP_038963480.1 Gene:Igf2bp3 / 312320 RGDID:1306512 Length:628 Species:Rattus norvegicus


Alignment Length:434 Identity:98/434 - (22%)
Similarity:182/434 - (41%) Gaps:88/434 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 TSSSAGGASIKHEDPSVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINI---SDGSCPER 67
            :|......|:..:.| ..|.:||::..:.||:||||:|..:....:::.:||::   .:....|:
  Rat   179 SSRQTSPGSVSKQKP-CDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENTGAAEK 242

  Fly    68 IVTV----SGTTNAIFSAFTLITKKFEEWCSQFNDVGKVGKTQIPIRLIVPASQCGSLIGKSGSK 128
            .:|:    .||:.|..|...::.|:.::  .:|.:       :||::::...:..|.||||.|..
  Rat   243 SITILSTPEGTSAACKSILEIMHKEAQD--IKFTE-------EIPLKILAHNNFVGRLIGKEGRN 298

  Fly   129 IKEIRQTTGCSIQVA--SEMLPNSTERAVTLSGSAEQITQCIYQICLVMLES------------P 179
            :|:|.|.|...|.::  .|:...:.||.:|:.|:.|...:...:|...:.||            .
  Rat   299 LKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNGLYH 363

  Fly   180 PRGATI----PYRPKPQVTGPVILANGQAFTIQGNYAVPTQETCPVFPLALATGGLHAGISGLAD 240
            |..|::    .:|...|.||..|     ...::..|      |..|||                 
  Rat   364 PLLASVSTGCTWRAAIQATGTSI-----HMYLRDKY------TDTVFP----------------- 400

  Fly   241 PLLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLAALGL----AGMNPASTGGINHTANPANRAQQ 301
               :|:.:...:.||           ..|..:|.||||    :||.|.::|..:....|..:.:|
  Rat   401 ---RGSCILPKLQAH-----------LIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQ 451

  Fly   302 QQHE---MTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVAL 363
            .:.|   :.:....:|.||||.|..|.::.:.:||.|:|:..|..:.  ..|.:.|:|.|::...
  Rat   452 SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA--KVRMVIITGPPEAQFK 514

  Fly   364 AQYLINMSVELQKANLLEQAQSQQNGGAAAAPGAAAAGVAAVTG 407
            ||..|  ..::::.|.:...:..:.......|..||..|....|
  Rat   515 AQGRI--YGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGG 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mubNP_001246875.1 PCBP_like_KH 25..86 CDD:239089 17/67 (25%)
PCBP_like_KH 109..172 CDD:239089 17/64 (27%)
KH-I 305..368 CDD:238053 19/65 (29%)
Igf2bp3XP_038963480.1 RRM_SF 1..77 CDD:418427
RRM2_IGF2BP3 81..156 CDD:410039
KH-I_IGF2BP3_rpt1 197..272 CDD:411920 18/76 (24%)
KH-I 275..359 CDD:412160 22/90 (24%)
KH-I_IGF2BP3_rpt3 451..528 CDD:411926 21/80 (26%)
KH-I_IGF2BP1_rpt4 536..611 CDD:411927 5/21 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166335337
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D394765at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.850

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