DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mub and Nova1

DIOPT Version :9

Sequence 1:NP_001246875.1 Gene:mub / 40436 FlyBaseID:FBgn0262737 Length:573 Species:Drosophila melanogaster
Sequence 2:XP_006240131.1 Gene:Nova1 / 298992 RGDID:621345 Length:507 Species:Rattus norvegicus


Alignment Length:485 Identity:119/485 - (24%)
Similarity:186/485 - (38%) Gaps:150/485 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 IRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISDG-----SCPERIVTVSGTTNAIFSAFTLI 85
            :::::.....||||||.|:.:.:.::|:||.|.:|..     ...||:..:.||..|:.:....|
  Rat    52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFI 116

  Fly    86 TKKFEEWCSQFNDVGKVGKTQ-------------------IP---------------------IR 110
            .:|..|...      .|.||:                   :|                     ::
  Rat   117 AEKIR
EMPQ------NVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVK 175

  Fly   111 LIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLP---NSTERAVTLSGSAEQITQCIYQIC 172
            :|||.|..|.:|||.|:.:|.|.:.:|..:|::.:  |   |..||.||:||..||..:.:..|.
  Rat   176 IIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELII 238

  Fly   173 LVMLESPPRGA--TIPYRPKPQVTGPVILANGQAFTIQGNYAVPTQETCPVFPLALATGGL--HA 233
            ..:.|.|..|:  .|.|   ..|||||..:|..        ..|...|..|.|.|.|..||  ||
  Rat   239 QKIQEDPQSGSCLNISY---ANVTGPVANSNPT--------GSPYANTAEVLPTAAAAAGLLGHA 292

  Fly   234 GISGLA--DPLLKG--------------------------------AHLQGAIPAHHHHLQQMPD 264
            .::|:|  ..:|.|                                |...||:.|        ..
  Rat   293 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA--------AA 349

  Fly   265 VAKNPLASLA------------------------ALGLAGMNPASTGGINHTANP---------- 295
            .:.||.|:.|                        |||......|:|.|....|:|          
  Rat   350 ASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTE 414

  Fly   296 -ANRAQQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPD 359
             :....:...|:.|..:|:|.|:||||..:.|.::::||.|:||...|...|..:|.:||:|.|.
  Rat   415 KSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPA 479

  Fly   360 SVALAQYLINMSVELQKANLLEQAQSQQNG 389
            :...|||||...:..::.  :..|..|:.|
  Rat   480 ATQAAQYLITQRITYEQG--VRAANPQKVG 507

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mubNP_001246875.1 PCBP_like_KH 25..86 CDD:239089 17/64 (27%)
PCBP_like_KH 109..172 CDD:239089 23/65 (35%)
KH-I 305..368 CDD:238053 25/62 (40%)
Nova1XP_006240131.1 KH-I 49..121 CDD:412160 19/68 (28%)
KH-I 172..241 CDD:412160 24/70 (34%)
KH-I 422..492 CDD:412160 27/69 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166335334
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.840

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