DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mub and rnc1

DIOPT Version :9

Sequence 1:	NP_001246875.1	Gene:	mub / 40436	FlyBaseID:	FBgn0262737	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_587684.1	Gene:	rnc1 / 2539434	PomBaseID:	SPCC757.09c	Length:	398	Species:	Schizosaccharomyces pombe

Alignment Length:	362	Identity:	100/362 - (27%)
Similarity:	166/362 - (45%)	Gaps:	71/362 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINISDG--SCPERIVTVSGTTNAIFSAFTLIT 86
            ||:|.::..:|.|.||||.|:.|...|..:..|..::..  :..:|::|:||....:..|:..|.
pombe    94 LTLRALLSTREAGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISGPLENVVRAYRFII 158

  Fly    87 KKFEEWCSQFNDVGKVGKTQIP--IRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPN 149
            ..|.:  :..|..|.......|  :||::..|..||:||::|.:||.|:....|.:..:.:|||.
pombe   159 DIFAK--NSTNPDGTPSDANTPRKLRLLIAHSLMGSIIGRNGLRIKLIQDKCSCRMIASKDMLPQ 221

  Fly   150 STERAVTLSGSAEQITQCIYQICLVMLESPPRGA-TIPYRPKPQVTGPV-ILANGQAFTIQGNYA 212
            ||||.|.:.|:.:.:...|::|...:::...||| |:.|.|..::|.|: .||         :.|
pombe   222 STERTVEIHGTVDNLHAAIWEIGKCLIDDWERGAGTVFYNPVSRLTQPLPSLA---------STA 277

  Fly   213 VPTQETCPVFPLALATGGLHAGISGLADP---LLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLA 274
            .|.|.:.|..|         :..||.|.|   :..||.:   .||......|.|.|.:|
pombe   278 SPQQVSPPAAP---------STTSGEAIPENFVSYGAQV---FPATQMPFLQQPKVTQN------ 324

  Fly   275 ALGLAGMNPASTGGINHTANPANRAQQQQHEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISN 339
                                           :::..|::|||||:||:||:|||:.||:.|.|:.
pombe   325 -------------------------------ISIPADMVGCIIGRGGSKISEIRRTSGSKISIAK 358

  Fly   340 CEEREGGNTDRTITISGNPDSVALAQYLINMSVELQK 376
            ....|.|  :|..||:|..:....|.:|:...:|::|
pombe   359 EPHDETG--ERMFTITGTHEENEKALFLLYQQLEMEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	PCBP_like_KH	25..86	CDD:239089	17/62 (27%)
		PCBP_like_KH	109..172	CDD:239089	22/62 (35%)
		KH-I	305..368	CDD:238053	24/62 (39%)
rnc1	NP_587684.1	PCBP_like_KH	95..158	CDD:239089	17/62 (27%)
		PCBP_like_KH	181..243	CDD:239089	22/61 (36%)
		KH-I	322..385	CDD:238053	25/101 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I3310
eggNOG	1	0.900	-	-		E1_KOG2190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001027
OrthoInspector	1	1.000	-	-		oto100936
orthoMCL	1	0.900	-	-		OOG6_103287
Panther	1	1.100	-	-	O	PTHR10288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1164
SonicParanoid	1	1.000	-	-		X408
TreeFam	1	0.960	-	-
	10	9.800