DRSC/TRiP Functional Genomics Resources

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Protein Alignment mub and Khsrp

DIOPT Version :10

Sequence 1:NP_001246875.1 Gene:mub / 40436 FlyBaseID:FBgn0262737 Length:573 Species:Drosophila melanogaster
Sequence 2:NP_001382025.1 Gene:Khsrp / 171137 RGDID:621828 Length:748 Species:Rattus norvegicus


Alignment Length:628 Identity:141/628 - (22%)
Similarity:219/628 - (34%) Gaps:165/628 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEDNNTSSS----AGGASIK------HEDPSVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGA 55
            :||.:...|    :.|.||.      |..|..::|....:....||.|||:.||.:|:.:::||.
  Rat   113 LEDGDQPDSKKLASQGDSIGSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGC 177

  Fly    56 KINIS--DGSCPERIVTVSGTTNAIFSAFTLITKKFEEWCS--------QFNDVGKVGKTQIPIR 110
            |:.||  .|..|||.|:::|...::..|..::    ::..|        ||:|....|:......
  Rat   178 KVQISPDSGGLPERSVSLTGAPESVQKAKMML----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 238

  Fly   111 LIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPN-STERAVTLSGSAEQITQCIYQICLV 174
            :::||.:.|.:|||.|..||::::..|..:.:..:...| :.::.:.:.|...::.|....:..:
  Rat   239 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDI 303

  Fly   175 MLESPP--------------RGATIPYRPKPQVTGPVILANGQAF-TIQGNYAVPTQETCPVFPL 224
            :.|...              .|..:|. |:..| |.||..:|:.. .||.:..|..|     |..
  Rat   304 LRERDQGGFGDRNEYGSRVGGGIDVPV-PRHSV-GVVIGRSGEMIKKIQNDAGVRIQ-----FKQ 361

  Fly   225 ALATGGLHAGISGLADPLLKGAHLQGAIPAHHHHLQQMPDVAKNPLASLAA-----LGLAGMNPA 284
            ...||.            .|.||:.|......|..:.:.|:    |.||.:     .|..||.|.
  Rat   362 DDGTGP------------EKIAHIMGPPDRCEHAARIINDL----LQSLRSGPPGPPGAPGMPPG 410

  Fly   285 STG---GINHTANPANRAQQQQHEMTVS--NDLIGCIIGKGGTKIAEIRQISGAMIRISNCEERE 344
            ..|   |..:...|..       |||.|  ....|.:||:||..:..|.|.:||.:.||......
  Rat   411 GRGRGRGQGNWGPPGG-------EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 468

  Fly   345 GGNTDRTITISGNPDSVALAQYLINMSVELQKANLLEQAQSQQNGGAAAAPGAAAAGVAAVTGAA 409
            |....:...|.|:|..:..|:.||...:|                                 |..
  Rat   469 GDPNFKLFVIRGSPQQIDHAKQLIEEKIE---------------------------------GPL 500

  Fly   410 APTSATNGAITTVTLTSGTGVVGAGAAGAAGVAN---------GANPAANGGGSNGTISATGYAS 465
            .|.              |.|..|.|.||..|..|         ||.|.| ||.........|:.:
  Rat   501 CPV--------------GPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHA-GGPPPHQYPPQGWGN 550

  Fly   466 ANGGQATNGSVGVNPAAAAALSSPLASALQLLTKPGALSALSNLSALDLLNLTTLGNTNGAGANP 530
            .............|.|||||            |.|.|..|    :..........|...|....|
  Rat   551 TYPQWQPPAPHDPNKAAAAA------------TDPNAAWA----AYYSHYYQQPPGPVPGPAPAP 599

  Fly   531 GGPPVQ-------TTGVNRAKGHYATSRFRQHQTETGGEAEKP 566
            ..||.|       .||    :..| |..:.::..:.|.:.::|
  Rat   600 AAPPAQGEPPQPPPTG----QSDY-TKAWEEYYKKIGQQPQQP 637

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mubNP_001246875.1 KH-I_PCBP_rpt1 26..92 CDD:411866 20/67 (30%)
KH-I_PCBP_rpt2 107..177 CDD:411806 13/70 (19%)
KH-I_PCBP_rpt3 301..371 CDD:411867 22/71 (31%)
KhsrpNP_001382025.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..148 8/34 (24%)
KH-I_FUBP2_rpt1 146..216 CDD:411907 22/73 (30%)
KH-I_FUBP2_rpt2 234..306 CDD:411910 13/71 (18%)
KH-I_FUBP2_rpt3 324..391 CDD:411913 21/89 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 394..422 7/27 (26%)
KH-I_FUBP2_rpt4 427..495 CDD:411916 22/67 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 498..570 21/86 (24%)
4 X 12 AA imperfect repeats 572..685 15/75 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 588..650 12/55 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 659..678
DUF1897 672..>686 CDD:462653
Blue background indicates that the domain is not in the aligned region.

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