Protein Alignment mub and IGF2BP2

DIOPT Version :10

• Sequence 1: NP_001246875.1
• Gene: mub / 40436
• FlyBaseID: FBgn0262737
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001278798.1
• Gene: IGF2BP2 / 10644
• HGNCID: 28867
• Length: 605
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 91/409 - (22%)
• Similarity: 175/409 - (42%)
• Gaps: 75/409 - (18%)

  Fly    11 GGASIKHEDPSVTLTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKINI---SDGSCPERIVTV- 71
            ||.|   :...:...:|:::..:.||:||||:|..:....:::.::::|   .:....|:.||:
Human   190 GGTS---QARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIH 251

  Fly    72 ---SGTTNAIFSAFTLITKKFEEWCSQFNDVGKVGKTQIPIRLIVPASQCGSLIGKSGSKIKEIR 133
               .||:.|......::.|:.:|        .|:.: :||::::......|.||||.|..:|:|.
Human   252 ATPEGTSEACRMILEIMQKEADE--------TKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIE 307

  Fly   134 QTTGCSIQVAS--EMLPNSTERAVTLSGSAEQITQCIYQICLVMLESPPRGATIPYRPKPQVTGP 196
            ..||..|.::|  ::...:.||.:|:.|:.|.......:|...:.|:              ....
Human   308 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA--------------FEND 358

  Fly   197 VILANGQAFTIQGNYAVPTQETCPVFPLALATGGLHA-GISGLADPLLKGAHLQGAIPAHHHHLQ 260
            ::..|.||..|.|              |.|:..|:.: |:|.|:.|    |..:||.||..:|
Human   359 MLAVNQQANLIPG--------------LNLSALGIFSTGLSVLSPP----AGPRGAPPAAPYH-- 403

  Fly   261 QMPDVAKNPLASLAALGLAGMNPASTGG--INHTANPANRAQQQQHEMTVSNDLIGCIIGKGGTK 323
                    |..:.:.. .:.:.|....|  .:|.:.|    :|:...:.:....:|.||||.|..
Human   404 --------PFTTHSGY-FSSLYPHHQFGPFPHHHSYP----EQEIVNLFIPTQAVGAIIGKKGAH 455

  Fly   324 IAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVALAQYLINMSVELQKANLLEQAQSQQN 388
            |.::.:.:||.|:|:..|..:  .::|.:.|:|.|::...||..|  ..:|::.|.....:..:.
Human   456 IKQLARFAGASIKIAPAEGPD--VSERMVIITGPPEAQFKAQGRI--FGKLKEENFFNPKEEVKL 516

  Fly   389 GGAAAAPGAAAAGVAAVTG 407
            ......|.:.|..|....|
Human   517 EAHIRVPSSTAGRVIGKGG 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mub	NP_001246875.1	KH-I_PCBP_rpt1	26..92	CDD:411866	16/72 (22%)
		KH-I_PCBP_rpt2	107..177	CDD:411806	20/71 (28%)
		KH-I_PCBP_rpt3	301..371	CDD:411867	20/69 (29%)
IGF2BP2	NP_001278798.1	RRM1_IGF2BP2	2..78	CDD:241070
		RRM2_IGF2BP2	82..163	CDD:410038
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..194		3/6 (50%)
		KH-I_IGF2BP2_rpt1	201..274	CDD:411919	16/72 (22%)
		KH-I_IGF2BP2_rpt2	282..358	CDD:411922	20/89 (22%)
		KH-I_IGF2BP2_rpt3	432..508	CDD:411925	22/79 (28%)
		KH-I_IGF2BP2_rpt4	515..592	CDD:411928	4/21 (19%)