Protein Alignment P5CDh1 and ALDH1A2

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_003879.2
• Gene: ALDH1A2 / 8854
• HGNCID: 15472
• Length: 518
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 138/463 - (29%)
• Similarity: 205/463 - (44%)
• Gaps: 63/463 - (13%)

  Fly   106 ADKKLIEKAI---KTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATM--LGQSKTAI 165
            |||..|:||:   :.|......|.|:..::|.::.:|.|||:.   |.....|||  |...|..:
Human    72 ADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVE---RDRAVLATMESLNGGKPFL 133

  Fly   166 QAEIDSAAELIDFIRMNAYFLKEV--------------TKYQPISENIKVTKNSLRYRGIDGFIA 216
            ||.......:|...|..|.:..::              |:::||                 |...
Human   134 QAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPI-----------------GVCG 181

  Fly   217 AVSPFNFTAIGGNLSYTPAL-MGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVF 280
            .:.|:||..:.......||| .||.|:.||::...||...:..:::|||.|.||:|.:|..||..
Human   182 QIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTA 246

  Fly   281 GDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVT 345
            |..|.:...:..|.||||......:.:..|.:     |..|:|.|.|||:.:.|.|.||::..|.
Human   247 GAAIASHIGIDKIAFTGSTEVGKLIQEAAGRS-----NLKRVTLELGGKSPNIIFADADLDYAVE 306

  Fly   346 STIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRI 410
            ...:..|...||.|:|.||::|.||::.:.....|..|.:..:|...|.::.....||.|.:.:|
Human   307 QAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKI 371

  Fly   411 -----TGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKE 470
                 :|..|.||    ||  .||.....||:|:.||:..:.....||..|||||||..|..:|.
Human   372 LELIQSGVAEGAK----LE--CGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT 430

  Fly   471 SDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRM 535
            .|  |.::..:.| .|.|..|||  ..|..|.......|.||..:||  ...::..|.||||.:|
Human   431 MD--EVIERANNS-DFGLVAAVF--TNDINKALTVSSAMQAGTVWIN--CYNALNAQSPFGGFKM 488

  Fly   536 SGTNDKAG 543
            ||...:.|
Human   489 SGNGREMG 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	138/463 (30%)
ALDH1A2	NP_003879.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	138/463 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810