Protein Alignment P5CDh1 and ALD5

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_010996.2
• Gene: ALD5 / 856804
• SGDID: S000000875
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 500
• Identity: 139/500 - (27%)
• Similarity: 229/500 - (45%)
• Gaps: 58/500 - (11%)

  Fly    77 IGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAI---KTAVETQPKWDRVSIADRLKIWE 138
            :..|:.||    :.|:...::.|:.:.|.|.:..:::|:   |.|.||  ||..|....|.|...
Yeast    53 VASKQKKT----FDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFET--KWSIVEPEVRAKALF 111

  Fly   139 KAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKY--------QPI 195
            ..|||: ..:::.|.|...:...|:...|..|.|.               |:||        ..|
Yeast   112 NLADLV-EKHQETLAAIESMDNGKSLFCARGDVAL---------------VSKYLRSCGGWADKI 160

  Fly   196 SENIKVT-KNSLRYR-----GIDGFIAAVSPFNFTAIGGNLSYTPAL-MGNGVLWKPSDTAMLSN 253
            ..|:..| ||...|.     |:.|   .:.|:||..:..:....||| .||.|:.||::|..||.
Yeast   161 YGNVIDTGKNHFTYSIKEPLGVCG---QIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSA 222

  Fly   254 WIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVN 318
            ....::.:|||:|.||||.:|..|.|.|:.::|.|.:..|.||||..|...:.|...:.:
Yeast   223 LFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTV----- 282

  Fly   319 FPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEA 383
             .::|.|.|||:.:.:.|.||::..|.:.....|...|:.|.|.||:|:.::::.::.:.|....
Yeast   283 -KKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYT 346

  Fly   384 AKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKD 448
            ..||:||..|...|..|...||...:|..|::.| ||....::.||....||||||.||:.....
Yeast   347 ESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVA-KSEGARLVTGGARHGSKGYFVKPTVFADVK 410

  Fly   449 PKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGN 513
            ...||:.||:|||::::..:...|  |.:.:.:.| ::.|...:  ...|..|......::.||.
Yeast   411 EDMRIVKEEVFGPIVTVSKFSTVD--EVIAMANDS-QYGLAAGI--HTNDINKAVDVSKRVKAGT 470

  Fly   514 FYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIK 558
            .:||  :..:.....||||...||.. :..|...:..:|..:|::
Yeast   471 VWIN--TYNNFHQNVPFGGFGQSGIG-REMGEAALSNYTQTKSVR 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	139/499 (28%)
ALD5	NP_010996.2	ALDH_F1-2_Ald2-like	41..513	CDD:143410	139/499 (28%)