Protein Alignment P5CDh1 and PUT2

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_011902.1
• Gene: PUT2 / 856432
• SGDID: S000001079
• Length: 575
• Species: Saccharomyces cerevisiae
• Alignment Length: 580
• Identity: 238/580 - (41%)
• Similarity: 340/580 - (58%)
• Gaps: 29/580 - (5%)

  Fly     9 SSRCSSLQQSLLKSSTRCLGSVIPDLKLKDFPIANEPILGYLK-DSKERKALEQALKGTASSCED 72
            |:||  |:....|.|...||.:.|...::     |||:..:.. |.|:...|..:|....||..:
Yeast     3 SARC--LKSIYFKRSFSQLGHIKPPKHIR-----NEPVKPFRNIDLKDWDLLRASLMKFKSSSLE 60

  Fly    73 IPIVIGGKEYKTPEVRY---QVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRL 134
            :|:||.|:.......|.   |..|.:||..||:...|.:|.:..|:|.|.:.:..|..:...||.
Yeast    61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRS 125

  Fly   135 KIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENI 199
            .|:.|||||::|.||.|:.|||||||.|...|||||...||.||.|....:..::...||: |:.
Yeast   126 AIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPV-ESA 189

  Fly   200 KVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREAG 264
            ..|.|...||.::||:.||||||||||..||...||||||.|:||||.||.|||:::..::.|||
Yeast   190 DGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAG 254

  Fly   265 VPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNI--DNYVNFPRLTGECG 327
            :|.||:||:|.|.....|.:.|......::||||...|..|:.::.:.:  ..|.::||:.||.|
Yeast   255 LPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319

  Fly   328 GKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPES------------LWPQIKEGLV 380
            |||||.:|.||::...|.||||..||:.||||||.||:|:|||            |..|....:.
Yeast   320 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMN 384

  Fly   381 CEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVL 445
            ..|:.:..|:::   .|...||.:::|.::...||.|||.|.||||.||.|..|:|:||.||::.
Yeast   385 TSASPISGGNLR---GFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIK 446

  Fly   446 SKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMA 510
            :|.|....|:.|.|||:|::|.|.:::..|...::..::::|||||:|.:|...::.|.::.|.:
Yeast   447 AKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFS 511

  Fly   511 AGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIKETFVPLRDVNYP 570
            |||||||||.||:||.||.|||.|||||:||||||:.:.|:.|.::.||.|..|.|..||
Yeast   512 AGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTDFKYP 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	225/539 (42%)
PUT2	NP_011902.1	D1pyr5carbox1	29..574	CDD:273517	229/552 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346304
Domainoid	1	1.000	397	1.000	Domainoid score	I89
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6081
Inparanoid	1	1.050	423	1.000	Inparanoid score	I283
Isobase	1	0.950	-	0	Normalized mean entropy	S619
OMA	1	1.010	-	-		QHG63568
OrthoFinder	1	1.000	-	-		FOG0004722
OrthoInspector	1	1.000	-	-		otm46911
orthoMCL	1	0.900	-	-		OOG6_102275
Panther	1	1.100	-	-	LDO	PTHR42862
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1040
SonicParanoid	1	1.000	-	-		X3320
TreeFam	1	0.960	-	-
	16	15.740