Protein Alignment P5CDh1 and Aldh8a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001178017.2
• Gene: Aldh8a1 / 685750
• RGDID: 1590218
• Length: 487
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 136/536 - (25%)
• Similarity: 232/536 - (43%)
• Gaps: 71/536 - (13%)

  Fly    54 KERKALEQALKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTA 118
            :|...||..:.|....|..   .|...:..|.|| |..:|:           :.|:.||.|::.|
  Rat     5 RELLMLENFIGGKFLPCNS---YIDSYDPSTGEV-YCKVPN-----------SGKEEIEVAVQAA 54

  Fly   119 VETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAE-IDSAAELIDFIRMN 182
            .|..|.|...|..:|..|..:.||::..:. ::|..|....|.||...|. :|....:::|
  Rat    55 REAFPAWSSRSPQERSLILNRVADVLEQSL-EELAQAESKDQGKTLTLARTMDIPRSVLNF---- 114

  Fly   183 AYFLKEVTKYQPISENIKVTK-NSLRYR-----GIDGFIAAVSPFNFTAIGGNLSYTPAL-MGNG 240
            .:|...:..:  :|:..:::. ..:.|.     ||.|.|   ||:|...........||: .||.
  Rat   115 RFFASSIQHH--VSDCTEMSHLGCMHYTVRTPVGIAGLI---SPWNLPLYLLTWKIAPAIAAGNT 174

  Fly   241 VLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRL 305
            |:.|||:...::.|:..|::.:||||.||:|.|...||..|:.:.:.|.:..|:||||.||..|:
  Rat   175 VIAKPSELTSVTAWMFCKLLDKAGVPPGVINVVFGTGPRVGEALVSHPEVPVISFTGSQPTAERI 239

  Fly   306 WKQVGNNIDNYVNFP---RLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYV 367
                     ..::.|   :|:.|.||||...|...|::|..:.:|:||:|...|:.|...||::|
  Rat   240 ---------TQLSAPHCKKLSLELGGKNPAIIFEDANLEECIPATVRSSFANQGEICLCTSRIFV 295

  Fly   368 PESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGG--- 429
            ..|::.:..:..|....|.|:|...|.|:...|:|.....:::..|:..| .:...:||.|.
  Rat   296 QRSIYNEFLKRFVEATRKWKVGIPSDPSANMGALISKAHLEKVRSYVTKA-HAEGAKILCGEGVD 359

  Fly   430 ----TYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTG 490
                ...:..|||:.||::.....:...|||||||||..:..:   |..|.:.......|:.|..
  Rat   360 QLSLPLRNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPF---DSEEEVIARANGVKYGLGA 421

  Fly   491 AVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQ 555
            .|:.:|...:....:  ::.:|..:.|......:  ..||||.:.||...:.....|
  Rat   422 TVWSKDVGRIHRVAK--RLQSGLVWTNCWLIREL--NLPFGGMKSSGIGREGAKDSY-------- 474

  Fly   556 SIKETFVPLRDVNYPY 571
               :.|..::.:...|
  Rat   475 ---DFFTEIKTITIKY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	135/526 (26%)
Aldh8a1	NP_001178017.2	ALDH_F8_HMSADH	27..485	CDD:143412	129/507 (25%)