Protein Alignment P5CDh1 and Aldh4a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001128170.1
• Gene: Aldh4a1 / 641316
• RGDID: 1624206
• Length: 562
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 332/559 - (59%)
• Similarity: 419/559 - (74%)
• Gaps: 5/559 - (0%)

  Fly    15 LQQSLLKSSTRCLGSVIPDLKLKDFPIANEPILGYLKDSKERKALEQALKGTASSCEDIPIVIGG 79
            |::|||..:.|  ||.:.........:||||||.:.:.|.||.||::||.......|.||.|:|.
  Rat     7 LRRSLLSYAWR--GSGLRWKHASSLKVANEPILAFTQGSPERDALQKALNDLKDQTEAIPCVVGD 69

  Fly    80 KEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLM 144
            :|..|.:||||:.|.:|.||:|.|.||||.|:.|||:.||..:.:||...:|||.:|:.||||::
  Rat    70 EEVWTSDVRYQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPVADRAQIFLKAADML 134

  Fly   145 ATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYR 209
            :...|.::.|.||:||.||.||||||:|||||||.|.||.|..|:...||||  :..:.|.:.||
  Rat   135 SGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPIS--VPPSTNHVVYR 197

  Fly   210 GIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVP 274
            |::||:||:||||||||||||:..||||||.|||||||||||:::.:::|:||||:|..|:.|||
  Rat   198 GLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNVIQFVP 262

  Fly   275 ADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASAD 339
            ||||.||||:|:|.||.|||||||||||..|||||..|:|.:..||||.||||||||||:|:|||
  Rat   263 ADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFRTFPRLAGECGGKNFHFVHSSAD 327

  Fly   340 VESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGD-VQDFSSFTSAVID 403
            |:|||:.|:||||||.|||||||||:|||:|||||||..|:.|.:::|:|: .:||.:|.|||||
  Rat   328 VDSVVSGTLRSAFEYGGQKCSACSRLYVPQSLWPQIKGRLLEEHSRIKVGNPAEDFGTFFSAVID 392

  Fly   404 DKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVY 468
            .|||.||..::|||:.||:|.|||||..::|.||||.|.|:.||||::.||.||||||||::|||
  Rat   393 AKAFARIKKWLEHARSSPSLSILAGGQCNESVGYFVEPCIIESKDPQEPIMKEEIFGPVLTVYVY 457

  Fly   469 KESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGG 533
            .:....||::||.::|.:.||||||.||:..|:.|.:..:.|||||||||||||||||||||||.
  Rat   458 PDEKYRETLQLVDSTTSYGLTGAVFAQDKTIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGA 522

  Fly   534 RMSGTNDKAGGPHYILRWTSPQSIKETFVPLRDVNYPYM 572
            |.||||||.|||||||||||||.||||..||.|..|.||
  Rat   523 RASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYM 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	319/522 (61%)
Aldh4a1	NP_001128170.1	ALDH_F4-17_P5CDH	31..552	CDD:143441	319/522 (61%)