Protein Alignment P5CDh1 and aldh4a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_957452.1
• Gene: aldh4a1 / 394133
• ZFINID: ZDB-GENE-040426-1179
• Length: 556
• Species: Danio rerio
• Alignment Length: 533
• Identity: 315/533 - (59%)
• Similarity: 415/533 - (77%)
• Gaps: 3/533 - (0%)

  Fly    41 IANEPILGYLKDSKERKALEQALKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYY 105
            :.|||:|.:.:.||||..||:||:......|:||.|||.:|..|.::|:|:.|.:|.|::|.|.|
Zfish    25 VKNEPVLEFKEGSKERAELEEALRNLKGKTEEIPCVIGNEEVWTKDIRFQLSPFNHSHQVAKFCY 89

  Fly   106 ADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEID 170
            |||.|:.|||:.:|..:.:||...::||.:|:.||||:::...|.::.|.||:||.||.:|||||
Zfish    90 ADKDLLNKAIEASVAARREWDLKPVSDRAQIFFKAADIISGPKRAEVLAKTMIGQGKTVVQAEID 154

  Fly   171 SAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPA 235
            :|.|||||.|.||....|:...||:..:  .:.|::.|||::||:|||:|||||||||||:.|||
Zfish   155 AAPELIDFFRFNAKHAIELEDQQPLDSD--GSTNTMLYRGLEGFVAAVAPFNFTAIGGNLAGTPA 217

  Fly   236 LMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVP 300
            ||||.||||||||||.:::.::||:||:|:|..::.||||||||||||:|:|.||||||||||||
Zfish   218 LMGNVVLWKPSDTAMSASYAVYKILRESGLPPNIIQFVPADGPVFGDTVTSSEHLAGINFTGSVP 282

  Fly   301 TFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRM 365
            ||.||||||..|:|.|.||||:.||||||||||:|.||||.||||.||||||||.||||||||||
Zfish   283 TFKRLWKQVAQNLDIYKNFPRVAGECGGKNFHFVHKSADVRSVVTGTIRSAFEYGGQKCSACSRM 347

  Fly   366 YVPESLWPQIKEGLVCEAAKLKIGD-VQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGG 429
            |||:||||||::||:....::|:|| |:|||:|.|||||||:|.||.|::|||:.||:|:|:|||
Zfish   348 YVPDSLWPQIRQGLLDVYKQIKVGDPVEDFSTFFSAVIDDKSFSRIKGWLEHARSSPHLKIIAGG 412

  Fly   430 TYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFG 494
            ...|.|||||.|||:.:.||:::||.||||||||::|||.|:|..:.:.|:..::.:|||||:|.
Zfish   413 NCDDKKGYFVEPTIIETTDPQEKIMNEEIFGPVLTVYVYPENDYKKVLHLIDNTSPYALTGAIFP 477

  Fly   495 QDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIKE 559
            ||:..::.|.:..:.||||:|||||||||:|.||||||.|.||||||.|||||:|||||||.:|:
Zfish   478 QDKSVIEEAGKALRNAAGNYYINDKSTGSIVAQQPFGGARASGTNDKPGGPHYVLRWTSPQVVKQ 542

  Fly   560 TFVPLRDVNYPYM 572
            |.|||.:..||||
Zfish   543 THVPLTEWKYPYM 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	308/522 (59%)
aldh4a1	NP_957452.1	ALDH_F4-17_P5CDH	25..546	CDD:143441	308/522 (59%)