DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment P5CDh1 and CG17896

DIOPT Version :9

Sequence 1:	NP_001189159.1	Gene:	P5CDh1 / 40434	FlyBaseID:	FBgn0037138	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_569845.2	Gene:	CG17896 / 30995	FlyBaseID:	FBgn0023537	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	547	Identity:	138/547 - (25%)
Similarity:	211/547 - (38%)	Gaps:	111/547 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 KALEQALKGTASSCEDIPIVIGGK--EYKTPEVRYQVMPHDHQHKLASFYYADK--KLIEKAIKT 117
            :|...|.:..:|:.....:.|.||  |.||.|   .:..||.    |:.....:  |..:..::.
  Fly    10 EARHLAKRSYSSAAPTTKLFIDGKFVESKTNE---WIDVHDP----ATNQVVTRVPKATQAEMQA 67

  Fly   118 AVETQPK----WDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAEL--- 175
            |:|:..|    |...||..|.::..|...|:.....:.....|. .|.||...||.|....|
  Fly    68 ALESNKKAFRSWSNQSILTRQQVMFKLQALIKENMGELAKNITK-EQGKTLADAEGDVLRGLQVV 131

  Fly   176 -----IDFIRMN---AYFLKEVTKYQ---PISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGN 229
                 |..::|.   |...:::..|.   |:                 |..|.|:||||.|:...
  Fly   132 EHCCSIPSLQMGETVANVARDMDTYSLVLPL-----------------GVTAGVAPFNFPAMIPL 179

  Fly   230 LSYTPAL-MGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPA--DGPVFGDTITASPHLA 291
            ..:..|: .||.:|.|||:....:..::.:::.|||.|.||||.:..  |...|   |..:|.:.
  Fly   180 WMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGVVNVIHGQHDAVNF---ICDAPEIK 241

  Fly   292 GINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCG 356
            .::|.||......::::.|.      |..|:....|.||...|...|:.|:.:.....:||...|
  Fly   242 AVSFVGSDQAGKYIYERAGK------NGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAG 300

  Fly   357 QKCSACS--------RMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGY 413
            |:|.|.|        :.::|:         ||..|.|||:.......:....||...:.:||...
  Fly   301 QRCMALSTAVFVGDAQAWIPD---------LVERAQKLKVNAGHVPGTDVGPVISAASRQRINDL 356

  Fly   414 IEHAKKSPNLEILAGGT-----YSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDL 473
            ||...|.....||.|..     |.|  ||||.|||:....|..:..|||||||||   |..::|.
  Fly   357 IESGVKEGAKLILDGRKITVPGYED--GYFVGPTILSDVTPSMKCYTEEIFGPVL---VILKADT 416

  Fly   474 LETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQP-------FG 531
            |:....:..:..:....|||..:.            ||...::|:...|.|....|       |.
  Fly   417 LDDAIGIVNANPYGNGTAVFTTNG------------AAARKFVNEIDAGQVGVNVPIPVPLPMFS 469

  Fly   532 GGRMSGTNDKAGGPHYILRWTSPQSIK 558
               .:||.....|.|:   :...|.||
  Fly   470 ---FTGTRGSFRGDHH---FYGKQGIK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	138/547 (25%)
CG17896	NP_569845.2	ALDH_F6_MMSDH	26..502	CDD:143404	135/531 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840