Protein Alignment P5CDh1 and Aldh5a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_074042.1
• Gene: Aldh5a1 / 291133
• RGDID: 621422
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 118/494 - (23%)
• Similarity: 207/494 - (41%)
• Gaps: 55/494 - (11%)

  Fly    77 IGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAA 141
            :||:...|| ..:.|.......||.:...........|::.|.:....|..:|:.:|..:..|..
  Rat    53 VGGRWLPTP-ATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAFSSWKEISVKERSSLLRKWY 116

  Fly   142 DLMATTYRQDLNAATMLGQSKTAI---QAEIDSAAELIDFIRMNAYFLKEVTK-YQPISENIKVT 202
            |||  ...:|..|..:..:|...:   |.||..:|..::      :|.:|..: |..|.......
  Rat   117 DLM--IQNKDELAKIITAESGKPLKEAQGEILYSAFFLE------WFSEEARRVYGDIIYTSAKD 173

  Fly   203 KNSLRYRGIDGFIAAVSPFNFTA------IGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMR 261
            |..|..:...|..:.::|:||.:      :|..|:     .|..|:.||::....|...:.::..
  Rat   174 KRGLVLKQPVGVASIITPWNFPSAMITRKVGAALA-----AGCTVVVKPAEDTPYSALALAQLAN 233

  Fly   262 EAGVPDGVVNFVPAD---GPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLT 323
            :||:|.||.|.:|..   ....|:.:...|.::.|:||||..|...|.....|::      .|::
  Rat   234 QAGIPPGVYNVIPCSRTKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSV------KRVS 292

  Fly   324 GECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLV---CEAAK 385
            .|.||.....:..||:|:..|...:.|.|...||.|...:|..|...    |.:..|   .||.|
  Rat   293 MELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRG----IHDSFVTKFAEAMK 353

  Fly   386 --LKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKD 448
              |::|:..:..:....:|::||.:::..::..| .:....::.||....|.|.|..||: ||..
  Rat   354 KSLRVGNGFEEGTTQGPLINEKAVEKVEKHVNDA-VAKGATVVTGGKRHQSGGNFFEPTL-LSNV 416

  Fly   449 PKDRI-MTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAG 512
            .:|.: :|||.|||:..:..:   |..|....:..:....|.|..:.||...:....::.::  |
  Rat   417 TRDMLCITEETFGPLAPVIKF---DKEEEAVAIANAADVGLAGYFYSQDPAQIWRVAEQLEV--G 476

  Fly   513 NFYINDKSTGSVVGQQPFGGGRMSG---TNDKAGGPHYI 548
            ...:|:....||  :.||||.:.||   ...|.|...|:
  Rat   477 MVGVNEGLISSV--ECPFGGVKQSGLGREGSKYGIDEYL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	118/494 (24%)
Aldh5a1	NP_074042.1	SSADH	66..516	CDD:188167	114/480 (24%)