Protein Alignment P5CDh1 and Aldh1a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_038949786.1
• Gene: Aldh1a1 / 24188
• RGDID: 2087
• Length: 520
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 140/492 - (28%)
• Similarity: 208/492 - (42%)
• Gaps: 96/492 - (19%)

  Fly   107 DKKLIEKAIKT---AVETQPKWDRVSIADRLKIWEKAADLM-------------------ATTYR 149
            ||..::||:|.   |.:....|..:..::|.::..|.||||                   |..|.
  Rat    75 DKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYL 139

  Fly   150 QDLN------------AATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVT 202
            .||.            |..:.||:       |.|..::..|           |:.:||
  Rat   140 SDLGGSIKALKYCAGWADKIHGQT-------IPSDGDIFTF-----------TRREPI------- 179

  Fly   203 KNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPAL-MGNGVLWKPSDTAMLSNWIIFKIMREAGVP 266
                      |....:.|:||..:.......||| .||.|:.||::...|:...:..:::|||.|
  Rat   180 ----------GVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFP 234

  Fly   267 DGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYV---NFPRLTGECGG 328
            .||||.||..||..|..|::...:..:.||||.        |||..|....   |..|:|.|.||
  Rat   235 PGVVNIVPGYGPTAGAAISSHMDVDKVAFTGST--------QVGKLIKEAAGKSNLKRVTLELGG 291

  Fly   329 KNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQD 393
            |:...:.|.||::..|.......|.:.||.|.|.||::|.||::.:.....|..|.|..:|:...
  Rat   292 KSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYVLGNPLT 356

  Fly   394 FSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEI 458
            ........||.:...:|...||..||. ..::..||....:||:||.||:..:...:.||..|||
  Rat   357 QGINQGPQIDKEQHDKILDLIESGKKE-GAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEI 420

  Fly   459 FGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDED---FVKCALQEFKMAAGNFYINDKS 520
            ||||..|..:|..|  :.:|..:.:| :.|...||.:|.|   .|..|||     ||..::|...
  Rat   421 FGPVQQIMKFKSID--DVIKRANNTT-YGLAAGVFTKDLDRAITVSSALQ-----AGVVWVNCYM 477

  Fly   521 TGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSI 557
            ..|  .|.||||.:||| |.:..|.|.:..:|..:::
  Rat   478 ILS--AQCPFGGFKMSG-NGRELGEHGLYEYTELKTV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	140/492 (28%)
Aldh1a1	XP_038949786.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	140/492 (28%)