Protein Alignment P5CDh1 and ALDH3A2

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001026976.1
• Gene: ALDH3A2 / 224
• HGNCID: 403
• Length: 508
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 108/457 - (23%)
• Similarity: 177/457 - (38%)
• Gaps: 119/457 - (26%)

  Fly   112 EKAIKTAVETQPKWDRVSIADRLKIWEKAADLMAT---TYRQDLNAATMLGQSKTAIQAEIDSAA 173
            ||.|.||:                    ||||..:   .|.|::  .|:||:
Human    38 EKDILTAI--------------------AADLCKSEFNVYSQEV--ITVLGE------------- 67

  Fly   174 ELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGID---------GFIAAVSPFNFTAIGGN 229
              |||:..|   |.|....:|:.:|:...        :|         |.:..:..:|:..:
Human    68 --IDFMLEN---LPEWVTAKPVKKNVLTM--------LDEAYIQPQPLGVVLIIGAWNYPFV--- 116

  Fly   230 LSYTPAL----MGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHL 290
            |:..|.:    .||.|:.|||:.:..:..|:.|::.:....|   .::..:|.|...|.......
Human   117 LTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQYLDQD---LYIVINGGVEETTELLKQRF 178

  Fly   291 AGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYC 355
            ..|.:||:......:.:....::      ..:|.|.|||:..:|....|::.|........:..|
Human   179 DHIFYTGNTAVGKIVMEAAAKHL------TPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNC 237

  Fly   356 GQKCSA-----CSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYIE 415
            ||.|.|     |......:.:| :||| .|.|.....|.:..|:    ..:|:.:.||||...:|
Human   238 GQTCIAPDYILCEASLQNQIVW-KIKE-TVKEFYGENIKESPDY----ERIINLRHFKRILSLLE 296

  Fly   416 HAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLV 480
            ..|       :|.|..:|....::.||::...|||.::|.||||||:|.|...|..|  |.:..:
Human   297 GQK-------IAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVD--EAINFI 352

  Fly   481 HTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQ----------PFGGGRM 535
            :...| .|...||..:...:|      :|      |::.|:|.|.|..          ||||...
Human   353 NEREK-PLALYVFSHNHKLIK------RM------IDETSSGGVTGNDVIMHFTLNSFPFGGVGS 404

  Fly   536 SG 537
            ||
Human   405 SG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	108/457 (24%)
ALDH3A2	NP_001026976.1	ALDH_F3AB	5..444	CDD:143450	108/457 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900