Protein Alignment P5CDh1 and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 112/473 - (23%)
• Similarity: 178/473 - (37%)
• Gaps: 131/473 - (27%)

  Fly   100 LASFYYADKKLIEKAI-----KTAVETQP-----KWDRVSIADR-LKIWEKAADLMATTYRQDLN 153
            |..|...:|:|:..|:     |:|.|::.     ....|::|.| |:.|.|       ..|...|
Human    33 LGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMK-------DERVPKN 90

  Fly   154 AATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAV 218
            .||           ::|||     |||...:                            |.:..:
Human    91 LAT-----------QLDSA-----FIRKEPF----------------------------GLVLII 111

  Fly   219 SPFNFTAIGGNLSYTPAL----MGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPV 279
            :|:|:..   ||:..|.:    .||.|:.|||:.:  .|  :.||:.|. :|..|      |...
Human   112 APWNYPL---NLTLVPLVGALAAGNCVVLKPSEIS--KN--VEKILAEV-LPQYV------DQSC 162

  Fly   280 FGDTITASPHLAG---------INFTGSVPTFNRLWKQVGNNIDNYV--NFPRLTGECGGKNFHF 333
            |. .:...|...|         |.||||        .:||..:....  :...:|.|.||||..:
Human   163 FA-VVLGGPQETGQLLEHRFDYIFFTGS--------PRVGKIVMTAAAKHLTPVTLELGGKNPCY 218

  Fly   334 IHASADVESVVTSTIRSAFEYCGQKCSA-----CSRMYVPESLWPQIKEGLVCEAAKLKI----G 389
            :..:.|.::|........:...||.|.|     ||         |:::|.|: .|.:..|    |
Human   219 VDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCS---------PEMQERLL-PALQSTITRFYG 273

  Fly   390 DVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIM 454
            |....|.....:|:.|.|:|:...:...:       :|.|..||....::.||:::.....:.:|
Human   274 DDPQSSPNLGRIINQKQFQRLRALLGCGR-------VAIGGQSDESDRYIAPTVLVDVQEMEPVM 331

  Fly   455 TEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDK 519
            .||||||:|.|...:..|  |.::.::...| .|....|......||..|.:  .::|.|..||.
Human   332 QEEIFGPILPIVNVQSLD--EAIEFINRREK-PLALYAFSNSSQVVKRVLTQ--TSSGGFCGNDG 391

  Fly   520 STGSVVGQQPFGGGRMSG 537
            .....:...||||...||
Human   392 FMHMTLASLPFGGVGASG 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	112/473 (24%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	112/473 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900