Protein Alignment P5CDh1 and Aldh5a1

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_766120.1
• Gene: Aldh5a1 / 214579
• MGIID: 2441982
• Length: 523
• Species: Mus musculus
• Alignment Length: 566
• Identity: 133/566 - (23%)
• Similarity: 223/566 - (39%)
• Gaps: 108/566 - (19%)

  Fly     6 RSSSSRCSSLQQSLLKSSTRCLGSVIPDLKLKDFPIANEPILGYLKDSKERKALEQALKGTASSC 70
            ||.:|....|...||:..:...|..:|  ....||: .:|..|             |..||.:.|
Mouse    33 RSYASGPGGLHADLLRGDSFVGGRWLP--APATFPV-YDPASG-------------AKLGTVADC 81

  Fly    71 EDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLK 135
                        ..||.|                        .|::.|.:....|..||:.:|..
Mouse    82 ------------GVPEAR------------------------AAVRAAYDAFNSWKGVSVKERSL 110

  Fly   136 IWEKAADLMATTYRQDLNAATML----GQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTK-YQPI 195
            :..|..|||... :.||  |.::    |:.....|.||..:|..::      :|.:|..: |..|
Mouse   111 LLRKWYDLMIQN-KDDL--AKIITAESGKPLKEAQGEILYSALFLE------WFSEEARRIYGDI 166

  Fly   196 SENIKVTKNSLRYRGIDGFIAAVSPFNFTA------IGGNLSYTPALMGNGVLWKPSDTAMLSNW 254
            .......|..|..:...|..|.::|:||.:      :|..|:     .|..|:.||::....|..
Mouse   167 IYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITRKVGAALA-----AGCTVVVKPAEDTPYSAL 226

  Fly   255 IIFKIMREAGVPDGVVNFVPAD---GPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNY 316
            .:.::..:||:|.||.|.:|..   ....|:.:...|.::.|:||||..|...|.....|::
Mouse   227 ALAQLANQAGIPAGVYNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSV--- 288

  Fly   317 VNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLV- 380
               .|::.|.||.....:..||:|:..|...:.|.|...||.|...:|..|...    |.:..|
Mouse   289 ---KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRG----IHDSFVT 346

  Fly   381 --CEAAK--LKIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNP 441
              .||.|  |::|:..:..:....:|::||.:::...:..| .:....::.||....|.|.|..|
Mouse   347 KFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDA-VAKGATVVTGGKRHQSGGNFFEP 410

  Fly   442 TIVLSKDPKDRI-MTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQ 505
            |: ||...:|.: :|||.|||:..:..:   |..|....:..:.:..|.|..:.||...:....:
Mouse   411 TL-LSNVTRDMLCITEETFGPLAPVIKF---DKEEEAVAIANAAEVGLAGYFYSQDPAQIWRVAE 471

  Fly   506 EFKMAAGNFYINDKSTGSVVGQQPFGGGRMSG---TNDKAGGPHYI 548
            :.::  |...:|:....||  :.||||.:.||   ...|.|...|:
Mouse   472 QLEV--GMVGVNEGLISSV--ECPFGGVKQSGLGREGSKYGIDEYL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	123/531 (23%)
Aldh5a1	NP_766120.1	SSADH	66..516	CDD:188167	123/531 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900