Protein Alignment P5CDh1 and alh-2

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_503467.2
• Gene: alh-2 / 187001
• WormBaseID: WBGene00000108
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 146/574 - (25%)
• Similarity: 228/574 - (39%)
• Gaps: 127/574 - (22%)

  Fly    15 LQQSLLKSSTR-----CLGSVIPDLKLKDFP-------IANEPILGYLKDSKERKALE------- 60
            :..|||:|:.|     |.||.:|. .|.||.       |.||.:     |:|..|..|
 Worm     1 MDSSLLRSAVRASVQACNGSGLPP-GLADFKPKYTSLFINNEFV-----DAKSGKTFEFVNPANG 59

  Fly    61 -QALKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPK 124
             ...|....:.:|:.|.:                                   :|.|.|.:...:
 Worm    60 KLLAKVAEGNRDDVDIAV-----------------------------------EAAKKAFKIGSE 89

  Fly   125 WDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQA-EIDSAAELIDFIRMNAYFLKE 188
            |.|:..:.|..:..:.||||... |..|.:...|...|...:| .||....:..|.....|..|.
 Worm    90 WRRMDASHRGVLLNRLADLMERD-RVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKN 153

  Fly   189 -------------VTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPAL-MGN 239
                         .|:::|:                 |....:.|:||..:.......||| |||
 Worm   154 HGKTIPVGGDYFTYTRHEPV-----------------GVCGQIIPWNFPLLMQAWKLAPALAMGN 201

  Fly   240 GVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNR 304
            .|:.|.:....||...:..:::||..|:||||.:|..|...|:.|.:...:..:.||||......
 Worm   202 TVVMKVAVKTPLSALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKT 266

  Fly   305 LWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPE 369
            :.|....:     |..::|.|.|||:.:.:.|.||:|..|..:..:.|...||.|||.||.:|..
 Worm   267 IMKAAAES-----NVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEG 326

  Fly   370 SLWPQIKEGLVCEAAKL----KIGDVQDFSSFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGT 430
            .::.:    .|.:|.:|    .|||..|.::.....||:...:.|..|||..||. ..:::.||.
 Worm   327 KIYDE----FVAKAKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKE-GAQLVTGGV 386

  Fly   431 YSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQ 495
            ....:||||.|||..:.:.:.:|..|||||||:.:..:   |.:|.:.....:|.:.|...|...
 Worm   387 KHGDQGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIRF---DSMEELIEKANNTIYGLAAGVVTN 448

  Fly   496 DEDFVKCALQEFK-MAAGNFYIN-----DKSTGSVVGQQPFGGGRMSGTNDKAG 543
            |   :..|||... :.||:.::|     |.:.       ||||.:.||...:.|
 Worm   449 D---LNKALQVANTIRAGSVWVNCYDVFDPAA-------PFGGFKQSGIGRELG 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	134/536 (25%)
alh-2	NP_503467.2	ALDH_F1-2_Ald2-like	34..507	CDD:143410	134/540 (25%)