Protein Alignment P5CDh1 and alh-3

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_502054.2
• Gene: alh-3 / 177999
• WormBaseID: WBGene00000109
• Length: 908
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 136/529 - (25%)
• Similarity: 231/529 - (43%)
• Gaps: 73/529 - (13%)

  Fly    41 IANEPILGYLKDSKERKALEQALKGTASSCEDIPIVIGGKEYKT--PEVRYQV--MPHDHQHKLA 101
            :..:||:..:.:.:.:...:|.:.|......|      |:.:||  |.....:  :|      ||
 Worm   410 VTYDPIVLNVNNMELKFPHDQFIDGKFVGSSD------GRTFKTINPATEKPICELP------LA 462

  Fly   102 SFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLM-------ATTYRQDLNAATMLG 159
            :....|:.:  :|.|.|.| :.:|.::|..:|.|...|.|:||       ||....|..|...|.
 Worm   463 TVADVDRAV--RAAKKAFE-RGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLA 524

  Fly   160 QSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQ----PISENIKVTKN-SLRYRGIDGFIAAVS 219
             .||.:...||          :..||.....|.|    ||| |.:..|| .|..|...|.:..::
 Worm   525 -LKTHVGMSID----------VWRYFAGWCDKIQGKTIPIS-NARPNKNLCLTLREPIGVVGLIT 577

  Fly   220 PFNFTAIGGNLSYTPA---LMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFG 281
            |:|:..:  .||:..|   ..||.|:.||:....|:.....::...||:|.||:|.|...|.:.|
 Worm   578 PWNYPLM--MLSWKMAACLAAGNTVVHKPAQVTPLTALKFAELSVLAGIPPGVINIVTGSGSLVG 640

  Fly   282 DTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYV---NFPRLTGECGGKNFHFIHASADVESV 343
            :.:||.|.:..|.||||.        ::|..:....   |..:::.|.|||:...|.|.||:|..
 Worm   641 NRLTAHPDVRKIGFTGST--------EIGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKA 697

  Fly   344 VTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFK 408
            |.....:.|...|:.|.|..|:::.:|:.....:.||.||.:.:|||..|.|:............
 Worm   698 VKQACGAVFFNKGENCIAAGRVFIAKSIHDDFVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLN 762

  Fly   409 RITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDL 473
            ::..|:|.| .:...::..||...:.:|.:..|||:.:.|.::...:||.|||::.:..:.:.|:
 Worm   763 KLVEYVEKA-VAGGAKVEVGGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDI 826

  Fly   474 LETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMA----AGNFYINDKSTGSVVGQQPFGGGR 534
            .:.::..: .|:|.|...||.:|..      :..::|    ||..::|......|..  ||||.:
 Worm   827 EDVLRRAN-DTEFGLAAGVFTRDSS------KSLRVAEALHAGTVFVNTYQKTDVAA--PFGGFK 882

  Fly   535 MSGTNDKAG 543
            .||.....|
 Worm   883 QSGFGKDMG 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	136/529 (26%)
alh-3	NP_502054.2	FMT_core_FDH_N	1..209	CDD:187716
		FDH_Hydrolase_C	214..315	CDD:187731
		PP-binding	335..393	CDD:425746
		ALDH-SF	423..908	CDD:448367	134/516 (26%)