Protein Alignment P5CDh1 and alh-6

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_493946.1
• Gene: alh-6 / 173510
• WormBaseID: WBGene00000112
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 303/571 - (53%)
• Similarity: 404/571 - (70%)
• Gaps: 12/571 - (2%)

  Fly     5 MRSSSSRCSSLQQSLLKSSTRCLGSVIPDLKLKDF--PIANEPILGYLKDSKERKALEQALKGTA 67
            |.|.::|.|.:.|       :|..|....|...||  ...|||||.|.|.||||:.||.||...:
 Worm     1 MLSFAARRSLITQ-------KCAASTYSGLTSADFLKKKTNEPILEYRKGSKERQDLEAALAFYS 58

  Fly    68 SSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIAD 132
            .:..::|:.||.|:......:.||:|.||:..||.:.||..:.|::||..|::.:..|:|..:.:
 Worm    59 KNITEVPLRIGDKKITNKLEQKQVIPSDHRSTLAKYTYATGEQIQEAIDVALQARGAWERKPLKE 123

  Fly   133 RLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISE 197
            |.:|..:||||.|..||..|||:|||||.|..||||||:|.|||||.|.||.|..|:..|:|||
 Worm   124 RAEILLRAADLAAGKYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYEPIS- 187

  Fly   198 NIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMRE 262
             .|:|||::::||::||:||::|||||||||||...||||||..|||||:||:|||:||::::.|
 Worm   188 -TKITKNTMQFRGMEGFVAAIAPFNFTAIGGNLPTAPALMGNVSLWKPSNTAVLSNYIIYELLEE 251

  Fly   263 AGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECG 327
            ||:|.|:::|:|:|||||||.|||||||:.:|||||||||..:|::|..|:||||.||:|.||||
 Worm   252 AGMPPGILSFLPSDGPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECG 316

  Fly   328 GKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQ 392
            ||||||:|.||.|::|...|.|||:||.|||||||||||.|:|:||:|.|.:.....::|:|||:
 Worm   317 GKNFHFVHPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEKISAIHKEIKLGDVR 381

  Fly   393 DFSSFTSAVIDDKAFKRITGYIEHAKK-SPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTE 456
            |.|.|.|||||||||.|:..||:.||. :....::.||...|..|||:.||::...|||.:::||
 Worm   382 DGSVFLSAVIDDKAFARLKAYIDFAKTGADGANVVLGGKCDDKTGYFIEPTLITVTDPKSKLLTE 446

  Fly   457 EIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKST 521
            |:||||:::.||::|.:.|.:..|..:|.:.||||||.||::|:..|....:.|.||.|:|||||
 Worm   447 EMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVLRDAVGNMYLNDKST 511

  Fly   522 GSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIKETFVPLRDVNYPYM 572
            ||:||||||||.|:||||||||||||.||||||.:||||.|.|.|..||.|
 Worm   512 GSIVGQQPFGGSRLSGTNDKAGGPHYGLRWTSPLTIKETSVSLTDWKYPSM 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	287/522 (55%)
alh-6	NP_493946.1	ALDH_F4-17_P5CDH	34..552	CDD:143441	287/519 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166854
Domainoid	1	1.000	557	1.000	Domainoid score	I119
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6081
Inparanoid	1	1.050	609	1.000	Inparanoid score	I498
Isobase	1	0.950	-	0	Normalized mean entropy	S619
OMA	1	1.010	-	-		QHG63568
OrthoDB	1	1.010	-	-		D293592at33208
OrthoFinder	1	1.000	-	-		FOG0004722
OrthoInspector	1	1.000	-	-		oto17933
orthoMCL	1	0.900	-	-		OOG6_102275
Panther	1	1.100	-	-	LDO	PTHR42862
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1040
SonicParanoid	1	1.000	-	-		X3320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890