Protein Alignment P5CDh1 and Aldh

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_313425.3
• Gene: Aldh / 1274323
• VectorBaseID: AGAMI1_004719
• Length: 515
• Species: Anopheles gambiae
• Alignment Length: 546
• Identity: 135/546 - (24%)
• Similarity: 238/546 - (43%)
• Gaps: 76/546 - (13%)

  Fly    59 LEQALKGTASSCEDIPIVIGGKEYKTPEVRYQ-VMPHDHQHK-----------------LASFYY 105
            |..|.:..::.|.:..:   .....:||:.|. :..::..||                 :|....
Mosquito     7 LSSAFRALSAHCRNYSV---PAPKSSPEILYTGIFINNEWHKSSTGKTFPTVNPSNEKVIAEIQQ 68

  Fly   106 ADKKLIEKAI---KTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSK---TA 164
            ..|..|::|:   :.|.:....|.|:..:.|.::..:.||||... |..|.:...|...|   .:
Mosquito    69 GTKADIDQAVVAARDAFKLGSPWRRMDASKRGQLLYRLADLMERD-RVYLASLETLDNGKPYFMS 132

  Fly   165 IQAEIDSAAELIDF------------IRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAA 217
            ...::..|...:.:            |.|:..|. ..|:::|:                 |....
Mosquito   133 YNVDVPMAISNLRYYAGWADKNHGKVIPMDGEFF-VYTRHEPV-----------------GVCGQ 179

  Fly   218 VSPFNFTAIGGNLSYTPAL-MGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFG 281
            :.|:||..:.....:.||| .||.::.||::...|:...:.::.:|||.|.||||.||..|.. |
Mosquito   180 IIPWNFPILMAAWKFGPALATGNTIILKPAEQTSLTALYMAQLTKEAGFPPGVVNVVPGYGDA-G 243

  Fly   282 DTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTS 346
            ..:...|.:..:.||||.....::  |.|:.:.   |..|.|.|.|||:.:.|.:.||::..|.:
Mosquito   244 AALVDHPDVDKVAFTGSTEVGKKI--QQGSGLS---NLKRTTLELGGKSPNIILSDADMKHAVET 303

  Fly   347 TIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRIT 411
            :....|...||.|.|.||.::.:.::.:..|.....|.|..:|:..|.::.....:|...:.:|.
Mosquito   304 SHFGLFFNMGQCCCAGSRTFIEDKIYDEFVERSAERAKKRTVGNPFDLTTEHGPQVDRAQYDKIL 368

  Fly   412 GYIEHAKKSPNLEILAGGT-YSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLE 475
            |.|:..|:. ...::|||: ..|..|||:.||:.........|..|||||||..:..:|..|  |
Mosquito   369 GLIDTGKQQ-GARLVAGGSKVPDLPGYFIQPTVFADVQDDMTIAQEEIFGPVQQLIRFKSLD--E 430

  Fly   476 TMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTND 540
            .::..: .|.:.|..|||.:|.|.|...:|..:  ||..::|..:..|  .|.||||.:||| :.
Mosquito   431 VIERAN-KTDYGLAAAVFSKDIDKVNYLVQGLR--AGTVWVNTYNVLS--AQAPFGGYKMSG-HG 489

  Fly   541 KAGGPHYILRWTSPQSIKETFVPLRD 566
            :..|.:.:..:|..:|: .|.:|:::
Mosquito   490 RENGEYGLQAYTEVKSV-ITRIPVKN 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	134/541 (25%)
Aldh	XP_313425.3	ALDH_F1AB_F2_RALDH1	30..509	CDD:143459	130/513 (25%)