Protein Alignment P5CDh1 and Aldh7a1

DIOPT Version :10

• Sequence 1: NP_649368.2
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_613066.2
• Gene: Aldh7a1 / 110695
• MGIID: 108186
• Length: 539
• Species: Mus musculus
• Alignment Length: 529
• Identity: 121/529 - (22%)
• Similarity: 211/529 - (39%)
• Gaps: 80/529 - (15%)

  Fly    41 IANEPILGYLKDSKERKALEQALKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYY 105
            :.:.|...:|:|...|:..|....|:          .||:    .||.....|.::: .:|....
Mouse    33 LIHHPQYAWLQDLGLREDNEGVYNGS----------WGGR----GEVITTYCPANNE-PIARVRQ 82

  Fly   106 ADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYR---QDLNAATMLGQSKTAIQ- 166
            |..|..|:.|..|.:....|..:....|.:|..|..|    .:|   |.|.....|...|..::
Mouse    83 ASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGD----AFREKIQLLGRLVSLEMGKILVEG 143

  Fly   167 -AEIDSAAELIDFI----RM----------NAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIA 216
             .|:....::.|:.    ||          ..:.|.|:  :.|:                 |.:.
Mouse   144 IGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEM--WNPL-----------------GLVG 189

  Fly   217 AVSPFNF-TAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMR---EAGVPDGVVNFVPADG 277
            .::.||| .|:.|..:....:.||..|||.:.|..|.:..:.||:.   |..:..|.:..:...|
Mouse   190 IITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGG 254

  Fly   278 PVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYV--NFPRLTGECGGKNFHFIHASADV 340
            ...|.|:.....:..::||||.        |||..:...|  .|.:...|.||.|.......||:
Mouse   255 ADIGTTMARDERVNLLSFTGST--------QVGKEVALMVQERFGKSLLELGGNNAIIAFEDADL 311

  Fly   341 ESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDK 405
            ..||.|.:.:|....||:|:...|:::.||:..::.:.|....:::::|:..|.:.....:...:
Mouse   312 SLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQ 376

  Fly   406 AFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKE 470
            |.......:|.|||... .::.||...|..|.:|.||||........|:.:|.|.|:|  ||:|.
Mouse   377 AVSMFVRAVEEAKKQGG-TVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPIL--YVFKF 438

  Fly   471 SDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVV-----GQQPF 530
            .|..|..:. :...|..|:.::|.:|...:...|.......|...:|..::|:.:     |::..
Mouse   439 QDEEEVFEW-NNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHT 502

  Fly   531 GGGRMSGTN 539
            ||||.||::
Mouse   503 GGGRESGSD 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_649368.2	ALDH_F4-17_P5CDH	41..563	CDD:143441	121/529 (23%)
Aldh7a1	NP_613066.2	ALDH_F7_AASADH	53..527	CDD:143448	116/509 (23%)