Protein Alignment P5CDh1 and aldh1l2

DIOPT Version :9

• Sequence 1: NP_001189159.1
• Gene: P5CDh1 / 40434
• FlyBaseID: FBgn0037138
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_002938116.1
• Gene: aldh1l2 / 100127737
• XenbaseID: XB-GENE-5820495
• Length: 922
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 140/593 - (23%)
• Similarity: 250/593 - (42%)
• Gaps: 99/593 - (16%)

  Fly     1 MLRMMRSSSSRCSSLQ---QSLLKSST--RCLGSVIPDLKLKDFPIANEPILGY----LKDSKER 56
            ::|::.....:|..|:   :.:..::|  ..:..|:..|:.:|   ..|.::.|    :.:...:
 Frog   378 VVRLVEELKQKCEGLELQNEDVYMATTFEEFIQMVVRKLRGED---KEELVIDYASLNVNNMTVK 439

  Fly    57 KALEQALKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQ--HKLASFYYADKKLIEKAIKTAV 119
            ...:..:.|..:..::      ||.|.|      :.|.|..  .|:|....||   ::||:..|.
 Frog   440 MPYQCFINGQFADADN------GKTYDT------INPTDGSVICKVAYCSVAD---VDKAVAAAK 489

  Fly   120 ET--QPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAA----ELIDF 178
            :.  ..:|.:::..||.:|..:.|||| ..::::|          ..|:| |||.|    .|...
 Frog   490 DAFENGEWGKMNARDRGRILYRLADLM-EEHQEEL----------ATIEA-IDSGAVYTLALKTH 542

  Fly   179 IRMNA----YFLKEVTKYQ----PISE-----NIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNL 230
            :.|:.    ||.....|.|    ||::     |:..||....     |..|.|.|:|:
 Frog   543 VGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPL-----GVCAIVIPWNY------- 595

  Fly   231 SYTPALM-----------GNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTI 284
               |.:|           ||.::.||:....|:.....::..:||||.||:|.:|..|.:.|..:
 Frog   596 ---PLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAVKAGVPKGVINILPGSGGLVGQRL 657

  Fly   285 TASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTIR 349
            :..|.:..:.||||.|...::.|....:     |..:::.|.|||:...|....|::..|...:.
 Frog   658 SEHPDIRKLGFTGSTPIGKQIMKSCAVS-----NLKKVSLELGGKSPLIIFNDCDLDKAVRMGMG 717

  Fly   350 SAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAKLKIGDVQDFSSFTSAVIDDKAFKRITGYI 414
            :.:...|:.|.|..|::|.||:..:....:|.|..|::|||..|.|:...........:::..|.
 Frog   718 AVYFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMRIGDPLDRSTDHGPQNHRAHLEKLLEYC 782

  Fly   415 EHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKL 479
            |...|. ...::.||......|:|:.||:....:....:..||.|||::.|..:|:.|:...::.
 Frog   783 EIGVKE-GATLVYGGRKVPRPGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGVLRR 846

  Fly   480 VHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAG- 543
            .: :|::.|...||  .:|..|......|:.||..:||..:...|..  ||||.:.||.....|
 Frog   847 AN-NTEYGLASGVF--TKDISKAMYVSEKLDAGTVFINTYNKTDVAA--PFGGFKQSGFGKDLGE 906

  Fly   544 -GPHYILR 550
             ..|..||
 Frog   907 EALHEYLR 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P5CDh1	NP_001189159.1	ALDH_F4-17_P5CDH	41..563	CDD:143441	133/548 (24%)
aldh1l2	XP_002938116.1	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..412	CDD:376348	4/33 (12%)
		ALDH_F1L_FTFDH	437..922	CDD:143458	131/531 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000