Protein Alignment Nopp140 and NOLC1

DIOPT Version :9

• Sequence 1: NP_001262195.1
• Gene: Nopp140 / 40433
• FlyBaseID: FBgn0037137
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: XP_005270330.1
• Gene: NOLC1 / 9221
• HGNCID: 15608
• Length: 710
• Species: Homo sapiens
• Alignment Length: 807
• Identity: 261/807 - (32%)
• Similarity: 333/807 - (41%)
• Gaps: 245/807 - (30%)

  Fly    11 IVLEYLQSKDKNLAKVFQQKTKAASVAKSSPKLSEILQFYQ--------------------TKSP 55
            :||.:|  :|..|::|..:..||....:.....|.:|..|.                    .|..
Human    17 LVLGFL--RDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLNRSAKVPERKLQANGPVAKKA 79

  Fly    56 KKIPAIKATAGDSSEDSDSDSESDAAPKKPATAPA----LTNGKAVKKAASS-----TSEDSDSE 111
            ||    ||::.||.:.|:.:.|....|.|.|..||    |..|||..||:.|     :|:|.|.|
Human    80 KK----KASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEE 140

  Fly   112 EEK--------KPAAKATPAKAVGKKAKS--SSEDSSSEEEAPK----KAAPV------KAP--P 154
            ::|        ||.|||  |||..|||||  |..|||||:|.||    |..||      |||  |
Human   141 DQKKQPVQKGVKPQAKA--AKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKP 203

  Fly   155 AKAAP------AKKVESSSEDSSSEEEPAKPAVKATTTKVAPAKKADSSSEESSSDEETKPAAKP 213
            |:|||      |....|||..|||.::..:....||..||...         :|...||.|..:.
Human   204 ARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKVWTI---------TSVRAETVPKKQV 259

  Fly   214 VAKAAPAKKA------ASSSEESDSDDEPAAKKP---------AVQPAAKPAPKAAASSSEDSSS 263
            ||| ||.|.|      :||||:|.||:|...|||         :|.|.:.|.||.:..:
Human   260 VAK-APVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGT------ 317

  Fly   264 EEEVKPAAKSAAKLAPAKKGASSSD--DSSSEDE-APKKAATLAKPISKAAPTKKA-----DSST 320
                :|..|:..|..|.:....|||  |||||:| .|...|.::|..:|..|.|||     |||.
Human   318 ----QPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD 378

  Fly   321 EDSSSEDDAPKKVAPAKATPAKAIPAKKAASSDDSSSEEEAPKKAAPANATPARAPP-------- 377
            .|||.:|:||.|  ||..|              .:||.:.|....:|| ..||.||.
Human   379 SDSSEDDEAPSK--PAGTT--------------KNSSNKPAVTTKSPA-VKPAAAPKQPVGGGQK 426

  Fly   378 --AKKAASS----DDSSSEEEAPKK-------AAPAKAT---PAKATP---AKKAASSDDSSSEE 423
              .:||.||    :.||||||..||       .|.|||.   |||..|   ...::.||.|||||
Human   427 LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEE 491

  Fly   424 EAPKKAAAPAKATPAKKAKSSSEDSDSDEEEAPKKPAAKAVAKA-----ASSEDSDSSEDEK--- 480
            |..|.:.:..|..|.|.|..:          ||.|||:....||     :||:||...|:||
Human   492 EEEKTSKSAVKKKPQKVAGGA----------APSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG 546

  Fly   481 ---PAKAAPKALAKSAKAASSDSDDSSDEETPAVKPAVKKTAAPAKKADSSSDESDSGEESGEVK 542
               |...||||...||..|.:.....:.||....|   ||.|....|             ||.:|
Human   547 KGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEK---KKAAVVVSK-------------SGSLK 595

  Fly   543 PNSATNGNEKTAQKRKFSGGDQDEATPNKKYNNFVKSGEQQKNDFTSTPNNTFSRNHNMNNSGGG 607
                         |||.:...::..||            |.|.....|| |||.:...     |.
Human   596 -------------KRKQNEAAKEAETP------------QAKKIKLQTP-NTFPKRKK-----GE 629

  Fly   608 SGRRSPFRRVRTEDVVVDSRVQDMSFEAKENDFKKHNNGRGGRGGSGFSGRPDRSTWETNKFNGE 672
            ....|||||||.|::.|||||.|.||:||             ||.:|..|  :|:. :..||.
Human   630 KRASSPFRRVREEEIEVDSRVADNSFDAK-------------RGAAGDWG--ERAN-QVLKFT-- 676

  Fly   673 GGGDGGGFKKIGDRKSFGGFDNNQRGG 699
               .|..|:....:|..|.:    |||
Human   677 ---KGKSFRHEKTKKKRGSY----RGG 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nopp140	NP_001262195.1	None
NOLC1	XP_005270330.1	SRP40_C	635..701	CDD:282829	31/87 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004782
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23216
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1974
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.130