Protein Alignment Nopp140 and NRPD1B

DIOPT Version :10

• Sequence 1: NP_001262195.1
• Gene: Nopp140 / 40433
• FlyBaseID: FBgn0037137
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_181532.2
• Gene: NRPD1B / 818591
• AraportID: AT2G40030
• Length: 1976
• Species: Arabidopsis thaliana
• Alignment Length: 739
• Identity: 152/739 - (20%)
• Similarity: 238/739 - (32%)
• Gaps: 212/739 - (28%)

  Fly    62 KATAGDSSEDSD---------SDSESDAAPKKPATAPALTNGKAVKKAASSTSEDSDSEEEKKPA 117
            |.|..|..|::|         |.:.:||                   ..||...|...||..:.|
plant  1234 KETGLDDKEETDVYSFLQMVISTTNADA-------------------FVSSPGFDVTEEEMAEWA 1279

  Fly   118 AKATPAKAVGK-KAKSSSEDSSSEEEAPKKAAPVKAPPAKAAPAKKVESSSEDSSSEEEPAKPAV 181
            .......|:|: |.:.|::..:..:|            .|.:.|...:|||.|:...........
plant  1280 ESPERDSALGEPKFEDSADFQNLHDE------------GKPSGANWEKSSSWDNGCSGGSEWGVS 1332

  Fly   182 KATTTKVAP----AKKADSSSEESSSDEETKPAAKPVAKAAPAKKAASSSEESDSDDEPAAKKPA 242
            |:|..:..|    .|..:...|::.|...|:..|:..:|:.........::::|:|..|..:
plant  1333 KSTGGEANPESNWEKTTNVEKEDAWSSWNTRKDAQESSKSDSGGAWGIKTKDADADTTPNWE--- 1394

  Fly   243 VQPAAKPAPKAAASSSEDSSSEEEVKPAA-----KSAA-----------KLAPAKKGAS------ 285
                ..||||       ||...|..:|.:     ||.:           :.|||..|::
plant  1395 ----TSPAPK-------DSIVPENNEPTSDVWGHKSVSDKSWDKKNWGTESAPAAWGSTDAAVWG 1448

  Fly   286 SSDDSSSEDEA--------PKKAATLAKPISKAAPTKKADSSTEDSSS---EDDAPKKVAPA--- 336
            |||..:||.|:        .|..:.:........|..|..|.||.:.:   ..|..|..|.|
plant  1449 SSDKKNSETESDAAAWGSRDKNNSDVGSGAGVLGPWNKKSSETESNGATWGSSDKTKSGAAAWNS 1513

  Fly   337 ---KATPAKAIPAKKAASSDDSSSEEEAP-------KKAAPANATPARAPPAKKAASSDDSSSEE 391
               |.....:.||...:....:|..|..|       ||.:.....||      .....|..:||.
plant  1514 WDKKNIETDSEPAAWGSQGKKNSETESGPAAWGAWDKKKSETEPGPA------GWGMGDKKNSET 1572

  Fly   392 EA--------PKKAAPAKATPAK--ATPAKKAASSDDSSSEEEAPKKAAAPAKATPAKKAKSSSE 446
            |.        .||.:..|:.||.  :|.|....|||.::||.|      :.|.|..::..|:|..
plant  1573 ELGPAAMGNWDKKKSDTKSGPAAWGSTDAAAWGSSDKNNSETE------SDAAAWGSRNKKTSEI 1631

  Fly   447 DSDSDEEEAPKKPAAKAVAKAASSEDSDSSEDEKPAKAAPKALAKSAKAASSDSDDSSDEETPAV 511
            :|.:....:..:|:..|       ||.|::||::    .|....|..|:...|..:.|....||.
plant  1632 ESGAGAWGSWGQPSPTA-------EDKDTNEDDR----NPWVSLKETKSREKDDKERSQWGNPAK 1685

  Fly   512 K-------------------------PAVKKTAAPAKKADSSSDESDSGEES---GEVKPNSATN 548
            |                         |..:...||...|.....:|.:.||.   .:|:|...|
plant  1686 KFPSSGGWSNGGGADWKGNRNHTPRPPRSEDNLAPMFTATRQRLDSFTSEEQELLSDVEPVMRT- 1749

  Fly   549 GNEKTAQKRKFSGG----DQDEATPNKKYNNFVKSGEQQKN---DFTSTPNNTFSRNHNMNNSGG 606
             ..|......:..|    |.|:....:|..||....|.:..   ||.:...:|.
plant  1750 -LRKIMHPSAYPDGDPISDDDKTFVLEKILNFHPQKETKLGSGVDFITVDKHTI----------- 1802

  Fly   607 GSGRRSPFRRVRTEDVV-VDSRVQDMSFEAKENDF------------------KKHNNGRGGRGG 652
                   |...|...|| .|...||.|:....|::                  |...:|...|..
plant  1803 -------FSDSRCFFVVSTDGAKQDFSYRKSLNNYLMKKYPDRAEEFIDKYFTKPRPSGNRDRNN 1860

  Fly   653 SGFSGRPDRSTWETNKFNGEGGGD 676
            ...:...:..:...|:..|.||.|
plant  1861 QDATPPGEEQSQPPNQSIGNGGDD 1884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nopp140	NP_001262195.1	None
NRPD1B	NP_181532.2	RNAP_IV_RPD1_N	24..798	CDD:259849
		RNAP_IV_NRPD1_C	825..1231	CDD:132724
		Ago_hook	<1462..1582	CDD:463088	24/125 (19%)
		DUF3223	1751..1827	CDD:431917	19/93 (20%)