Protein Alignment Nopp140 and dpy

DIOPT Version :10

• Sequence 1: NP_001262195.1
• Gene: Nopp140 / 40433
• FlyBaseID: FBgn0037137
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Alignment Length: 687
• Identity: 121/687 - (17%)
• Similarity: 229/687 - (33%)
• Gaps: 155/687 - (22%)

  Fly    18 SKDKNLAKVFQQKTKAASVAKSSPKLSEILQFYQTKSPKKIPAI----KATAGDSSEDSDSDSES 78
            |.:..:..|..:.|....:..:..:::|    ..|.||.::...    ::|....|.|..:.|||
  Fly  6102 SLETTVPSVTLETTTNVPIGSTGGQVTE----QTTSSPSEVRTTIRVEESTLPSRSADRTTPSES 6162

  Fly    79 DAAPKKPATAPALTNGKAVKKAASSTSEDSDSEEEKKPAAKATPAKAVGKKAKSSSEDSSSEEEA 143
                  |.| |.|.:....:..:..|:|.:......:|...:||:.| ..:....|..|.:....
  Fly  6163 ------PET-PTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPA-SLETTVPSVTSETTTNV 6219

  Fly   144 P------KKAAPVKAPPAKAAPAKKVES------SSEDSSSEEEPAKPAVKATTTKVAPAKKADS 196
            |      :......|||::......||.      |::.:|..|.|..|....:.....|
  Fly  6220 PIGSTGGQVTGQTTAPPSEVRTTIGVEESTLPSRSTDRTSPSESPETPTTLPSDFITRP------ 6278

  Fly   197 SSEESSSDEETKPAAKPVAKAAPAKKAASSSEESDSDDEPAAKKPAVQPAAKPAPKAAASSS--- 258
            .||:::......|..:|...:.|:               ||:.|..|......|.......|
  Fly  6279 HSEQTTESTRDVPTTRPFEASTPS---------------PASLKTTVPSVTSEATTNVPIGSTGG 6328

  Fly   259 ----EDSSSEEEVKPAAKSAAKLAPAKKGASSSDDSSSEDEAPKKAATLAKPISKAAPTKKADSS 319
                :.:||..||:...:......|     |.|.|.::..|:|:...||....:....::|...|
  Fly  6329 QVTEQTTSSPSEVRTTIRVEESTLP-----SRSTDRTTPSESPETPTTLPSDFTTRPHSEKTTES 6388

  Fly   320 TEDSSS----EDDAPKKVAPAKATPAKAIPAKKAASSDDSSSEEEAPKKAAPANA-TPARAPPAK 379
            |.|..:    |...|...:.....|:..:....:.....:..:......|.|:.. |..|...:.
  Fly  6389 TRDVPTTRPFETSTPSPASLETTVPSVTLETTTSVPMGSTGGQVTGQTTAPPSEVRTTIRVEEST 6453

  Fly   380 KAASSDDSSSEEEAPKKAAPAKATPAK------ATPAKKAASSDDSSSEEEAPKKAAAPAKATPA 438
            ..:.|.|.:|..|:|:       ||..      ..|..:..:..........|.:|:.|:.|:..
  Fly  6454 LPSRSTDRTSPSESPE-------TPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASSG 6511

  Fly   439 KKA----------------KSSSEDSDSDEEEAPKKPAAKAVAKAASSEDSDSSED---EKPAKA 484
            ...                :|:...:.|:..|.|..| :....:..|.:.::|:.|   .:|.:|
  Fly  6512 NNCSISYFRNHYKCSNRFNRSADRTTPSESPETPTLP-SDFTTRPHSEQTTESTRDVPTTRPFEA 6575

  Fly   485 APKALAKSAKAASSDSDDSSDEETPAVKPAVKKTAAPAKKADSSSD---ESDSGEESGEV----- 541
            :                      ||:  ||..:|..|:..::::::   .|..|:.:|:.
  Fly  6576 S----------------------TPS--PASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPS 6616

  Fly   542 KPNSATNGNEKTAQKRKFSGGDQDEATPNKKYNNFVKSGEQQ---KNDFTSTPNN--TFSRNHNM 601
            :..:.....|.|...|     ..|..||:       :|.|..   .:|||:.|::  |.....::
  Fly  6617 EVRTTIRVEESTLPSR-----STDRTTPS-------ESPETPTILPSDFTTRPHSDQTTESTRDV 6669

  Fly   602 NNSGGGSGRRSPFRRVRTEDVVVDSRVQDMSFEAKEN 638
            ..:       .||.......|.:::.|..::.|...|
  Fly  6670 PTT-------RPFEASTPRPVTLETAVPSVTLETTTN 6699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nopp140	NP_001262195.1	None
dpy	NP_001260032.1	EGF_3	137..166	CDD:463759
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:463759
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		Herpes_BLLF1	<4032..4489	CDD:282904
		Herpes_BLLF1	<4334..4797	CDD:282904
		PHA03255	4845..>5021	CDD:165513
		DUF5585	4959..5356	CDD:465521
		PHA03247	<5170..5799	CDD:223021
		PRK12495	<5749..5877	CDD:183558
		PHA03247	<5865..6485	CDD:223021	79/427 (19%)
		Chi1	6385..>6609	CDD:442692	40/255 (16%)
		Herpes_BLLF1	<6607..7102	CDD:282904	20/112 (18%)
		Herpes_BLLF1	<7027..7490	CDD:282904
		DUF5585	7550..7954	CDD:465521
		DUF5585	7881..>8130	CDD:465521
		Atrophin-1	18652..>19081	CDD:460830
		PHA03247	<18873..19514	CDD:223021
		ZP	22576..22811	CDD:214579