Protein Alignment Nopp140 and dao-5

DIOPT Version :10

• Sequence 1: NP_001262195.1
• Gene: Nopp140 / 40433
• FlyBaseID: FBgn0037137
• Length: 773
• Species: Drosophila melanogaster
• Sequence 2: NP_001021004.1
• Gene: dao-5 / 266845
• WormBaseID: WBGene00000931
• Length: 971
• Species: Caenorhabditis elegans
• Alignment Length: 908
• Identity: 333/908 - (36%)
• Similarity: 413/908 - (45%)
• Gaps: 306/908 - (33%)

  Fly    21 KNLAKVFQQKTKAASVAKS---SPKLSEILQFYQTKSPKKIPAIKATAGDSSEDSDSDSESDAAP 82
            |..|...|:|.:::|.:.|   :.||:.:      |.|.:.||.|..|  ||.|||||   |..|
 Worm   105 KKSATPVQKKAESSSSSDSDAPAKKLTPV------KKPAQTPAQKKAA--SSSDSDSD---DEPP 158

  Fly    83 KKPATAPALT-------------------------NGKA-------------------VKKAASS 103
            ||   |||:|                         :||:                   .||||||
 Worm   159 KK---APAVTTKVAPKPMAKKQDTSDSDSDSEDSDDGKSKKANPVKVTPVANVLQKVVAKKAASS 220

  Fly   104 TSEDSDSEEEKKPAAKATPA----KAVGKKAKSSSEDSSSEEE-----APKKA------------ 147
            :|:.||  :|||||||.|||    |.|.|||:|||:.|..|::     ||.||
 Worm   221 SSDSSD--DEKKPAAKPTPAKPTPKPVVKKAESSSDSSDDEKKPVAKPAPAKATPKPAAKKADSS 283

  Fly   148 -------APVKAPPAKAAP---AKKVESSSEDSSSEEEPAKPAVKATTTKVAP---AKKADSSSE 199
                   ||.|..||||||   |||.|||| |||.:|:  |||.|.|..|..|   ||||:|||:
 Worm   284 SDSSDDEAPAKKTPAKAAPKPVAKKAESSS-DSSDDEK--KPAAKPTPAKATPKPVAKKAESSSD 345

  Fly   200 ESSSDEETKPAAKPV-AKAAP---AKKAASSSEESDSDDEPAAKKPAVQPAAKPAPKAAASSSED 260
              |||:|.||.|||. |||.|   ||||.|||:.||.:.:||||....:...||..|.|.|||:
 Worm   346 --SSDDEKKPVAKPAPAKATPKPVAKKAESSSDSSDDEKKPAAKPTPAKATPKPVAKKAESSSD- 407

  Fly   261 SSSEEEVKPAAK-SAAKLAP---AKKGASSSDDSSSEDEAPKKAATLAKPISKAAP---TKKADS 318
             ||::|.||.|| ::||..|   |||..||||  ||:||||.|     |..:||||   :|||:|
 Worm   408 -SSDDEKKPVAKPTSAKATPKPAAKKADSSSD--SSDDEAPAK-----KTPAKAAPKPASKKAES 464

  Fly   319 STEDSSSEDDAPKKVAPAKATPAKAIP---AKK-AASSDDSSSEEEAP-KKAAPANATPARAPPA 378
            |::  ||:|:.|    .||:||||..|   ||| |:||.|||.:|:.| .|..||||||  .|.|
 Worm   465 SSD--SSDDEKP----AAKSTPAKITPKPTAKKVASSSSDSSDDEKKPAAKPTPANATP--KPVA 521

  Fly   379 KKAASSDDSSSEEEAP---------------KKA----------APAKATPAKATP---AKKAAS 415
            |||.||.|||.:|:.|               |||          ||||.|||||.|   :|||.|
 Worm   522 KKAESSSDSSDDEKKPVAKPTSAKATPKPAAKKADLSSDFSDDEAPAKKTPAKAAPKPASKKAES 586

  Fly   416 SDDSSSEEEAPKKAAAPAKATP---AKKAKSSSEDSDSDEE---------EAPKKPAAKAVAKAA 468
            |.| ||::|.|...:.|||.||   ||||.|||.||..||:         :|..|||||....::
 Worm   587 SSD-SSDDEKPAAKSTPAKTTPKPTAKKAASSSSDSSDDEKKPVAKPTSAKATPKPAAKKADSSS 650

  Fly   469 SSED-------------------------SDSSEDEK------PAKAAPKALAKSAKAASSD--- 499
            .|.|                         ||||:|||      |.|..||::.|.|.|:|||
 Worm   651 DSSDDEAPAKKTPVKPTPVKIVAKKVDSSSDSSDDEKKPTKATPVKVTPKSVTKKAAASSSDSSD 715

  Fly   500 -----------------------SDDSSDEE-TPAVKPAVKKT-AAPAKKADSSSDESD------ 533
                                   ||||||:| .|..||..|.| ...|||||||.|.||
 Worm   716 DEKKPVVKQTPNVVPKKEKAASSSDDSSDDEKKPTAKPTPKATPKQSAKKADSSDDSSDDEAPAK 780

  Fly   534 -------------------SGEESGE---VKPNSAT---NGNEKTAQKRKFS--GGDQDE----- 566
                               |.::|.:   .|..|||   ....|||.|:..|  ..|.||
 Worm   781 KTPAKSTPAKTAVKKEASSSSDDSSDDEKTKKKSATTPAKSTPKTALKKAESSDSSDDDEDLPKP 845

  Fly   567 ---ATPNKKYNNFVKSGEQQKND-----------FTSTPNNTFSRNHNMNNSGGGSGRRSPFRRV 617
               .||..:..:..:|.|.:::.           .|||....:.....         :.||||||
 Worm   846 SKAVTPRPQRADSEESAETEESSSRTPALKAKPLATSTEKAVYENRKR---------KSSPFRRV 901

  Fly   618 R-TEDVVVDSRVQDMSFEAKENDFKKHNNGRGGRGGSGFSGRPDRSTWETNKFNGEGGGDGGG 679
            : |:|.|        |.:.:.|....|.:..|.|..... |:.....:...|...:.|..|||
 Worm   902 QMTKDSV--------SEKFRNNQHDSHFDQWGQRANESL-GKVVGKAFRHEKTKKKKGSYGGG 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nopp140	NP_001262195.1	None
dao-5	NP_001021004.1	PRK12323	<245..457	CDD:481241	109/225 (48%)
		PRK12323	<389..606	CDD:481241	108/234 (46%)
		PHA03247	<445..886	CDD:223021	160/454 (35%)
		SRP40_C	897..966	CDD:461525	19/68 (28%)