DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7148 and SKP2B

DIOPT Version :9

Sequence 1:	NP_649366.1	Gene:	CG7148 / 40432	FlyBaseID:	FBgn0046301	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001185415.1	Gene:	SKP2B / 844036	AraportID:	AT1G77000	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	330	Identity:	68/330 - (20%)
Similarity:	116/330 - (35%)	Gaps:	94/330 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YEQLDLEKWRVLLPNHEDL-VYFLTQMRPYI--REMGGSSCLCSILKDLDEMHIAELPMVTSFYY 115
            :|.:.:|  .||:...:|: |..|.::...:  |.:..:||:||..:|...:.:..|.:..
plant    15 FENMKME--GVLISEWKDIPVELLMKILNLVDDRTVIIASCICSGWRDAVSLGLTRLSLSW---- 73

  Fly   116 DPDGVDCYPTNRSIRKLARLLPGLKKLRLTTPIDGRYLSNFQHLQELHLYEDQHKAFELQQKYLD 180
                  |.....|:  :..|.|                 .|..||.|.|.:|:.   :|:...::
plant    74 ------CKKNMNSL--VLSLAP-----------------KFVKLQTLVLRQDKP---QLEDNAVE 110

  Fly   181 EVCRTLHDLRVLDIRTYDMISKLQLGNCLQSFKNLTDLKLNLATLKPILPAVLE--LPSLRKLVV 243
            .:....|:|:.||:.....|:...|.:..:...|||  ||||:.........|.  ....|||.:
plant   111 AIANHCHELQDLDLSKSSKITDHSLYSLARGCTNLT--KLNLSGCTSFSDTALAHLTRFCRKLKI 173

  Fly   244 LLDNEWHIPPLVSPDSYDHKIREVSEFYEIMAFKAKDIVGFAVDGYYMPLEPGWDEKLP------ 302
            |  |.......||    |:.::.:.|....:                ..|..||.|.:.
plant   174 L--NLCGCVEAVS----DNTLQAIGENCNQL----------------QSLNLGWCENISDDGVMS 216

  Fly   303 -IWTHRRLKRLAICSWTHSADYLKRYTCMTELQLLCVRNWNDLSDEILLEFVELCPRLEHLDVSY 366
             .:....|:.|.:||                    ||.    ::||.::.....|..|..|.:.|
plant   217 LAYGCPDLRTLDLCS--------------------CVL----ITDESVVALANRCIHLRSLGLYY 257

  Fly   367 CRNLT 371
            |||:|
plant   258 CRNIT 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7148	NP_649366.1	leucine-rich repeat	333..358	CDD:275381	5/24 (21%)
SKP2B	NP_001185415.1	F-box	28..63	CDD:395521	9/34 (26%)
		leucine-rich repeat	66..91	CDD:275381	6/53 (11%)
		leucine-rich repeat	92..118	CDD:275381	6/28 (21%)
		AMN1	<115..264	CDD:187754	43/196 (22%)
		leucine-rich repeat	119..144	CDD:275381	5/24 (21%)
		leucine-rich repeat	145..170	CDD:275381	7/26 (27%)
		leucine-rich repeat	171..197	CDD:275381	7/31 (23%)
		leucine-rich repeat	198..223	CDD:275381	4/40 (10%)
		leucine-rich repeat	224..249	CDD:275381	9/48 (19%)
		leucine-rich repeat	250..272	CDD:275381	7/13 (54%)
		leucine-rich repeat	294..319	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010