DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7148 and VFB2

DIOPT Version :9

Sequence 1:	NP_649366.1	Gene:	CG7148 / 40432	FlyBaseID:	FBgn0046301	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_566928.1	Gene:	VFB2 / 824170	AraportID:	AT3G50080	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	444	Identity:	94/444 - (21%)
Similarity:	162/444 - (36%)	Gaps:	146/444 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LDDDCLAEIFDRLQDLPSEVSFARTCRRVQYICLSKW-----RTSHAYEQLDLEKWRVLLP---- 67
            |.|||||.||..|     .....:.|..|.    .:|     :..|   :|.|:....:||
plant    44 LPDDCLAHIFQFL-----SAGDRKRCSLVS----KRWLLVDGQNRH---RLSLDAKSEILPFLPC 96

  Fly    68 --NHEDLV-----------YFLTQMRPYIREMGGSSCL------CSILKDLDEMHIAELPMVTSF 113
              |..|.|           :.|:....:|..:..|:.:      |..:.||
plant    97 IFNRFDSVTKLALRCDRRSFSLSDEALFIVSIRCSNLIRVKLRGCREITDL-------------- 147

  Fly   114 YYDPDGVDCYPTN-RSIRKLA--RLLPGLKKLRLTTPIDGRYLSNFQHLQELHL--YEDQHKAFE 173
                 |::.:..| :|:|||:  ....|.|.:       ...|.:.:.|:||.|  ....|:..|
plant   148 -----GMESFARNCKSLRKLSCGSCTFGAKGI-------NAMLEHCKVLEELSLKRIRGLHELAE 200

  Fly   174 ---------LQQKYLDEV-----------CRTLHDLRVLD-IRTYDMISKLQLGNCLQSFKNL-- 215
                     |:..:|.|:           .|||..::::. :..:|.:.::. ||...|...:
plant   201 PIKLSLSASLRSVFLKELVNGQVFGSLVATRTLKKVKIIRCLGNWDRVFEMN-GNGNSSLTEIRL 264

  Fly   216 -----TDLKL-------NLATLKPI---------LPAVLE-LPSLRKLVVLLDNEWHIPPLVSPD 258
                 ||:.|       ||.||..:         |.:|:| ...||||.:   :.|.:..:
plant   265 ERLQVTDIGLFGISKCSNLETLHIVKTPDCSNLGLASVVERCKLLRKLHI---DGWRVKRI---- 322

  Fly   259 SYDHKIREVSEFYEIMAFKAKDIVGFAVDGYYMPLEPGWDEKLPIWTH-RRLKRLAICSWTHSAD 322
             .|..:..|::.    ....:::|...||..||.|.       .|.:: ::|:|||:|......|
plant   323 -GDQGLMSVAKH----CLNLQELVLIGVDATYMSLS-------AIASNCKKLERLALCGSGTIGD 375

  Fly   323 YLKRYTCMTE----LQLLCVRNWNDLSDEILLEFVEL-CPRLEHLDVSYCRNLT 371
              ....|:.|    |:..|::..  |..::.::.:.| ||:|..|.|..|..:|
plant   376 --AEIGCIAEKCVTLRKFCIKGC--LISDVGVQALALGCPKLVKLKVKKCSLVT 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7148	NP_649366.1	leucine-rich repeat	333..358	CDD:275381	5/25 (20%)
VFB2	NP_566928.1	F-box-like	42..>71	CDD:403981	11/35 (31%)
		AMN1	<119..>187	CDD:187754	15/93 (16%)
		leucine-rich repeat	133..158	CDD:275381	5/43 (12%)
		leucine-rich repeat	159..183	CDD:275381	6/30 (20%)
		leucine-rich repeat	233..258	CDD:275381	4/25 (16%)
		leucine-rich repeat	259..282	CDD:275381	3/22 (14%)
		AMN1	263..>410	CDD:187754	36/169 (21%)
		leucine-rich repeat	283..308	CDD:275381	6/24 (25%)
		leucine-rich repeat	309..336	CDD:275381	7/38 (18%)
		leucine-rich repeat	337..361	CDD:275381	7/30 (23%)
		leucine-rich repeat	362..387	CDD:275381	8/26 (31%)
		leucine-rich repeat	388..412	CDD:275381	5/25 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010