DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7148 and CG14317

DIOPT Version :9

Sequence 1:	NP_649366.1	Gene:	CG7148 / 40432	FlyBaseID:	FBgn0046301	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_650675.1	Gene:	CG14317 / 42161	FlyBaseID:	FBgn0038566	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	117/498 - (23%)
Similarity:	215/498 - (43%)	Gaps:	114/498 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLILQLDDDC------------------LAEIFDRLQDLPSEVSFARTCRRVQYICLSKWRTSHA 53
            :|:.|.::.|                  ..:||:.:.:|..:|..||...:.....|..|:
  Fly    13 ALVAQQNNTCSPMEEIEPNYIDNLHIIFFEQIFEEIDNLIDQVRMARAYPQFMPQILKFWQ---- 73

  Fly    54 YEQLDLEKWRVLLPNH--------EDLVYFLTQMRPYIREM------GGSSCLCSILKDLDEMHI 104
             .:|.|    ::.||.        :|.|:|:..|.....::      |..|.....:..|.:::|
  Fly    74 -RRLHL----IIGPNTPFLGLLDIDDYVFFMEHMADSFTDLHVHDGVGSFSEFYDYITHLCDINI 133

  Fly   105 AELPMVTSFYY--DPDGVDCYPTNRSIRKLARLLPGLKKLRLTTPIDGRYLSNFQHLQELHLYED 167
            .:.|.|.:...  :|:.|    .:..||.|..:||.||:|.....:.|.|:..|:.|:|| ::..
  Fly   134 TKFPKVDTCILAGNPNTV----VDEDIRDLTVMLPNLKRLMTCMNLSGLYMRGFKKLEEL-VFNS 193

  Fly   168 QHKAFELQQKYLDEVCRTLHDLRVLDIRTYDMISKLQLGNCLQ----SFKNLTDLKLNLATLKPI 228
            .:.:..|..:::.::|.|:.:||||||..       |..:|::    ...||..||:||:|::.:
  Fly   194 LYHSVPLDSRWIQDICLTMTNLRVLDITD-------QFDSCVRLTDIKLPNLEVLKINLSTVECM 251

  Fly   229 LPAVLELPSLRKLVVLLDNEWHIPPLVSPDSYDHKIREVSEFYEIMAFKAKDIVGFAVDGYYMPL 293
            |..||:||.|:||.|..|           ||......:.:.|.:|:..|::.|...|::...:.|
  Fly   252 LSEVLQLPKLQKLSVRFD-----------DSRQLNADQETIFQQIVVAKSERITRIALNNEVVQL 305

  Fly   294 EPGWDE----KLPIWTHRRLKRLAICSWTHSADYLKR--YTCMTELQLLCVRNWNDLSDEILLEF 352
            ...|.:    :||     :|:::...:|.|:..:|.|  ..|. ::::|....|..:.:..|||.
  Fly   306 PARWQQSLLLELP-----KLRKVICENWCHNDFFLDRQHMPCQ-QMEVLSFSGWEIVRETQLLEL 364

  Fly   353 VELCPRLEHLDVS-YCRNLTPTFLPRALSILKRREPFKQKTGVGRSP-PLKLYYDLSGFEDFVDR 415
            |..|..||||.:: |..|...  |.:.::|..:.          |:| ||:::.|:. :.:|...
  Fly   365 VAECVNLEHLALNGYHSNWEK--LTKLVNIRNQE----------RNPRPLQVFSDMM-WGNFTPE 416

  Fly   416 ANLKSSLEY-----RGYIVFTADFPVDSERGLSFVDRGYQFEF 453
                   ||     ..|:..|.|   .||  ..:.:.|::|:|
  Fly   417 -------EYYHWQSNKYVQVTCD---SSE--YEYQEDGFEFDF 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7148	NP_649366.1	leucine-rich repeat	333..358	CDD:275381	7/24 (29%)
CG14317	NP_650675.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447172
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0016901
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930