Protein Alignment CG7148 and FBXW8

DIOPT Version :9

• Sequence 1: NP_649366.1
• Gene: CG7148 / 40432
• FlyBaseID: FBgn0046301
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_016874665.1
• Gene: FBXW8 / 26259
• HGNCID: 13597
• Length: 599
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 44/225 - (19%)
• Similarity: 72/225 - (32%)
• Gaps: 93/225 - (41%)

  Fly   185 TLHDLRVLDIRTYDMI-------------------------SKLQLGNCLQSFKNLTDLKLNL-- 222
            |..|:||.|.||:|.:                         |.|.:......|.|:.||:...
Human   229 TSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLNIWDLRTGKYP 293

  Fly   223 -------ATLKPIL----PAVLELPSLRKLVVLLDNE---WHI------PPLVS-----PDSYDH 262
                   |.::.:.    .|.:...|...:|:|..||   |.|      |.||.     |::..:
Human   294 VHRFEHDARIQALALSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVPKLVQYLEIVPETRRY 358

  Fly   263 KIREVSEFYEIMAFKAKDI---------------------VGFAVDGYYMPLEPGW---DEKLPI 303
            .:...:....:...||:|.                     |.|.|.|.      ||   ..|:.:
Human   359 PVAVAAAGDLMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGVQGL------GWVYEGSKILV 417

  Fly   304 WT---HRRLKRLAICSWTHSADYLKRYTCM 330
            ::   .|||.:|        .:.|:.:||:
Human   418 YSLEAGRRLLKL--------GNVLRDFTCV 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7148	NP_649366.1	leucine-rich repeat	333..358	CDD:275381
FBXW8	XP_016874665.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1046098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010