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Protein Alignment CG7148 and FBXL2

DIOPT Version :9

Sequence 1:	NP_649366.1	Gene:	CG7148 / 40432	FlyBaseID:	FBgn0046301	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001336245.1	Gene:	FBXL2 / 25827	HGNCID:	13598	Length:	454	Species:	Homo sapiens

Alignment Length:	402	Identity:	84/402 - (20%)
Similarity:	149/402 - (37%)	Gaps:	138/402 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SFARTCRRVQYI------------CLSKWRTSHAYEQLDLEKWRVLLPNHEDLVYFLTQMRPYIR 84
            :||:.||.::::            |.|..|.....:.|||... |.:.|               .
Human    98 TFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSC-VSITN---------------S 146

  Fly    85 EMGGSSCLCSILKDLDEMHIAELPMVTSFYYDPDGVDCYPTNRSIRKLARLLPGLKKLRL--TTP 147
            .:.|.|..|   ::|:.::::....:|.     ||::.         |.|...|||.|.|  .|.
Human   147 SLKGISEGC---RNLEYLNLSWCDQITK-----DGIEA---------LVRGCRGLKALLLRGCTQ 194

  Fly   148 IDG---RYLSNFQH-LQELHLYEDQHKAFELQQKYLDEVCRTLHDLRVLDIRTYDMISKLQLGNC 208
            ::.   :::.|:.| |..|:|    .....:..:.:.::||..|.|:.|               |
Human   195 LEDEALKHIQNYCHELVSLNL----QSCSRITDEGVVQICRGCHRLQAL---------------C 240

  Fly   209 LQSFKNLTD-----LKLNLATLKPILPAV-------------------LELPSLRKLVVLLDN-- 247
            |....||||     |.||...|: ||.|.                   ||...|.:.:::.|:
Human   241 LSGCSNLTDASLTALGLNCPRLQ-ILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTL 304

  Fly   248 ---EWHIPPLVSPDSYDHKIREVSEFYEIMAFKAKDIVGFAVDGYYMPLEPGWDEKLPIWTHRRL 309
               ..|.|.|.:                :::....||:      :.:.:      |.|...:::|
Human   305 IQLSIHCPKLQA----------------LVSLSFSDII------HLLKM------KEPSHHNKKL 341

  Fly   310 KRLAIC-SWTH----SAD---YLKRYTCMTE-LQLLCVRNWNDLSDEILLEFVELCPRLEHLDVS 365
            ...:.| |.:|    :.|   :|...||..| |::|.:.|...::| :.||.:|.|..||.|::.
Human   342 FGFSFCKSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITD-VALEHLENCRGLERLELY 405

  Fly   366 YCRNLTPTFLPR 377
            .|:.:|...:.|
Human   406 DCQQVTRAGIKR 417

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.