Protein Alignment eIF2A and AT1G73180

DIOPT Version :10

• Sequence 1: NP_649365.1
• Gene: eIF2A / 40431
• FlyBaseID: FBgn0037135
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_565058.1
• Gene: AT1G73180 / 843652
• AraportID: AT1G73180
• Length: 513
• Species: Arabidopsis thaliana
• Alignment Length: 538
• Identity: 163/538 - (30%)
• Similarity: 262/538 - (48%)
• Gaps: 78/538 - (14%)

  Fly    10 PTLAI--RSSVAVELWSSAGSKQPFEH-KPHLPREETKSSRSICFSSNGRYFAYSNGQEVKVLQA 71
            |:|.|  |.:....:|:.    .||.: :|.|..|....|.: .||.:|.          |::..
plant     5 PSLEILVREAEGFTVWNG----PPFTNGQPTLKLERVSCSNT-KFSVDGS----------KLMAM 54

  Fly    72 SRDSAASWPVICVLPRPKAFYL------QFSPRGSYLCTWEHYAITKDRPEGSPNLLVYEVATGV 130
            ..|...|......|...::|.:      :.||.|:||.|::.....:::     |:.::...||.
plant    55 KSDGVISIYDATSLTEVRSFTIANVTAAELSPCGTYLQTFQKPTTPQEK-----NVSIWNTETGD 114

  Fly   131 EVFAIVQKN--QADWQPS--WSADESIFALVVGGEALFYDLGEGAEKGFA--TTSR-KIGGSRGG 188
            ...:..||:  :|.| ||  :..|||....:...|..|:|     .|.|:  .||| ::.|....
plant   115 LAHSHYQKSITKASW-PSIRFCPDESSACRLATNEVQFFD-----PKDFSKGITSRIRVPGIAAF 173

  Fly   189 MLSLGPGNCPPFLAFYTPGAKGAPSMCKLYKYPALGQNQTVACKSFFQADRVEMLWNKRGSGLLL 253
            .||..|.:   .:|.:.|.:||:|...:::......|:|..|.:|||:...|:..||...:|||:
plant   174 ELSKTPAS---HVAVFVPESKGSPGSVQIFGCGEELQSQPSARRSFFRCSSVQFSWNHGSTGLLV 235

  Fly   254 LTSTEVDKSGASYYGNQAVHFMATKG-DTCSVPLSKEGPVHCVKWSPKATEFVVVYGFMPSKAAL 317
            :..::|||:..||||...:|::...| ....|||.||||||.|:||...:||.|||||||:...:
plant   236 VVQSDVDKTNQSYYGETKLHYLTIDGTHEGLVPLRKEGPVHDVQWSFSGSEFAVVYGFMPACVTI 300

  Fly   318 YNLKCDVVFDFGEGPRNCAYFNPFGNLIALAGFGNLPGAVEVWDVSKREKLANLKCADTTVFEWH 382
            ::..|..:.:.||||.|...:||.|.::.:||||||||.:..|||..:::|.:.|...:...||.
plant   301 FDKNCKPLMELGEGPYNTLRWNPKGRVLCVAGFGNLPGDMAFWDVVNKKQLGSNKAEWSVTSEWS 365

  Fly   383 PNGEWFVTATTAPRLRISNGFKVYHYSGALLHETMWPQGQELLGIEW-----QQFAD-----KTF 437
            |:|.:|:||:||||.:|.||.|:::|.|...::.|:   :.|...||     ::|.|     |:.
plant   366 PDGRYFLTASTAPRRQIDNGMKIFNYDGKRYYKKMF---ERLYQAEWKPESPERFGDISELIKSV 427

  Fly   438 SEPKITKAKHEGIKSSQ-------PEASK-KAYTPPHLRLLKEGKNPEKYLPQPSIPGLAPTAAA 494
            ...|:.:.|.:|..|:|       |.|.| .||.|||.:        .....|..:.|::.|
plant   428 ESLKLGEGKSQGQGSAQKKTIAPNPIAQKPAAYRPPHAK--------HAAAVQAELLGISTT--- 481

  Fly   495 GGVNGNKRNNKNKQRSAR 512
            |.::.|...||.|:.:.:
plant   482 GEMSKNALKNKKKRENKK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2A	NP_649365.1	COG5354	13..636	CDD:227657	161/535 (30%)
		eIF2A	232..418	CDD:462552	78/186 (42%)
		WD40 repeat	292..327	CDD:293791	15/34 (44%)
		WD40 repeat	334..371	CDD:293791	16/36 (44%)
		WD40 repeat	376..399	CDD:293791	11/22 (50%)
AT1G73180	NP_565058.1	COG5354	19..486	CDD:227657	155/509 (30%)
		eIF2A	214..407	CDD:462552	80/195 (41%)
		WD40 repeat	280..312	CDD:293791	12/31 (39%)
		WD40 repeat	317..352	CDD:293791	15/34 (44%)